Gliwice Scientific Meetings Twenty Years

Gliwice Scientific Meetings Twenty Years 1997-2016.

Dear Friends and Colleagues, This year we celebrate the twentieth anniversary of the Gliwice Scientific Meetings. The prehistory of this series of annual conferences includes irregular scientific meetings organized in the 60s, 70s and 80s by Prof. Mieczysław Chorąży and his team from the Department of Tumor Biology at the Institute of Oncology in Gliwice. In 1997, Prof. Joanna Rzeszowska-Wolny and her team from the newly established Department of Experimental and Clinical Radiobiology at the Institute of Oncology decided to continue this tradition of scientific meetings. From the beginning, the organizational and financial backbone for these events was provided by the Association for the Support of Cancer Research, an entity founded by researchers from the Institute of Oncology and colleagues from the Silesian University of Technology. Today the Gliwice Scientific Meetings are organized jointly by the Institute of Oncology and the Silesian University of Technology the two major scientific centers located in Gliwice. More recently, the Polish Group of the EACR also contributes to the scientific program of the conference. The Gliwice Scientific Meetings are focused on different aspects of cancer research, molecular and cellular biology, and medicine, biotechnology and bioinformatics. During the last twenty years more than 350 lecturers from all parts of the world have contributed to the scientific excellence of our conference. The conference has hosted about 1500 participants who presented about 1000 posters. We believe that during these years the Gliwice Scientific Meeting established a solid scientific reputation, and became a recognizable event not only for Polish researchers. On the occasion of the twentieth anniversary we would like to express our warm gratitude to all participants, co-organizers and sponsors of the conference. But the story will be continued, and hence we also invite you to future Gliwice Scientific Meetings. Yours sincerely, Prof. Joanna Rzeszowska-Wolny Prof. Piotr Widłak

Organizers of Gliwice Scientific Meetings: Association for the Support of Cancer Research, Gliwice Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch Silesian University of Technology, Gliwice

Co-organizers and Patronage of Gliwice Scientific Meetings in years 1997-2016 Gliwice Municipal Office Silesian Voivodship Marshal s Office Ministry of Science and Higher Education Polish Academy of Sciences European Association for Cancer Research * * * Mayor of Gliwice Marshal of Silesian Voivodship Rector of Silesian University of Technology Director of MSC Cancer Center and Institute of Oncology, Gliwice Branch

Members of Scientific Committees of Gliwice Scientific Meetings in years 1997-2016 Peter Bannasch (Heidelberg) Andrzej Bednarek (Łódź) Wojciech Cholewa (Gliwice) Mieczysław Chorąży (Gliwice) Franck Delaunay (Nice) Jan Filipski (Paris) Zbigniew Grzywna (Gliwice) Ron Hancock (Quebec) Kari Hemminki (Heidelberg) Jőrg Hoheisel (Heidelberg) Roman Jaksik (Gliwice) Barbara Jarząb (Gliwice) Bożena Kamińska (Warszawa) Andrzej Karbownik (Gliwice) Marek Kimmel (Houston) Stanisław Kochowski (Gliwice) Witold Konopka (Warszawa) Zdzisław Krawczyk (Gliwice) Marek Los (Linköping) Bogusław Maciejewski (Gliwice) Danuta Mielżyńska (Sosnowiec) Korneliusz Miksch (Gliwice) Carmel Mothersill (Hamilton) Andrzej Polański (Gliwice) Jarosław Polański (Katowice) Joanna Polańska (Gliwice) Joanna Rzeszowska-Wolny (Gliwice) Jerzy Rutkowski (Gliwice) Martin Simard (Quebec) Stanisław Szala (Gliwice) Wiesław Szeja (Gliwice) Krzysztof Szyfter (Poznań) Dorota Ścieglinska (Gliwice) Andrzej Świerniak (Gliwice) Maciej Ugorski (Wrocław) Piotr Widłak (Gliwice) Ryszard Wilk (Gliwice)

Members of Organizing Committees of Gliwice Scientific Meetings in years 1997-2016 Alicja Bebel-Baron Beata Bęben Artur Cieślar-Pobuda Iwona Domińczyk Sylwia Drzewiecka Agnieszka Dudło Agnieszka Gdowicz-Kłosok Jakub Hanus Robert Herok Roman Jaksik Dorota Janicka Magdalena Kalinowska-Herok Izabela Kołodziejczyk Anna Lalik Jolanta Leonarczyk Joanna Łanuszewska Halina Miazgowicz Aleksandra Miodońska Aneta Oprzondek Monika Pietrowska Wojciech Pigłowski Lucyna Ponge Jacek Rogoliński Joanna Rzeszowska-Wolny Aleksandra Szczerbik Magdalena Skonieczna Aleksander Sochanik Sebastian Student Katarzyna Szołtysek Anna Walaszczyk Piotr Widłak Elżbieta Zielińska-Król

1997 GSM pre-conference in Srebrna Góra 2016 GSM-2016, ACK Mrowisko GSM-2016: Piotr Widłak and Joanna Rzeszowska Joanna Rzeszowska, Mieczysław Chorąży, Piotr Widłak

Scientific Programs of Gliwice Scientific Meetings in years 1997-2016

(I) Gliwickie Spotkania Naukowe 1997 Oddziaływania białko DNA 21-22.11.1997 Modelowanie układów biologicznych Bogdan Lesyng: Jak modelować układy biomolekularne; od miareczkowania do dynamiki kwantowej. Andrzej Polański: Niesymetryczna segregacja w modelach genetyki popularnej. Rafał Tarnawski: Modele radiobiologiczne stosowane w praktyce klinicznej. Oddziaływania białko-dna w procesach transkrypcji i replikacji Ewa Bartnik: TBP - Struktura i rola w transkrypcji Grzegorz Węgrzyn: Rola podjednostki alfa polimerazy RNA E. coli w inicjacji i antyterminacji transkrypcji. Jolanta Zakrzewska: Oddziaływania białka DnaA z regionem inicjującym replikację DNA. Jarosław Marszałek: Rola nukleotydów adeninowych w oddziaływaniach białka inicjatorowego DnaA z DNA. Jerzy Majka: Badanie oddziaływania białka DnaA z regionem inicjującym replikację DNA za pomocą techniki SPR. Igor Konieczny: Oddziaływania białek replikacyjnych a zmiany konformacji DNA podczas inicjacji replikacji plazmidu RK2. Dagmara Jakimowicz: Izolacja regionu oric za pomocą chromatografii powinowactwa. Uszkadzanie i śmierć komórek Ewa Sikora: Mechanizmy śmierci komórek indukowanej kurkuminą (składnik curry); udział czynników transkrypcyjnych. Krzysztof Szyfter: Ryzyko genetyczne w raku krtani określone na podstawie rozkładu genotypów baterii enzymów odpowiedzialnych za metabolizm kacerogenów. Marcin Kruszewski: Rekombinacja homologiczna DNA w komórkach ssaków upośledzonych w naprawie uszkodzeń DNA. Nowe techniki Wojciech Markiewicz: Syntetyczne oligonukleotydowe biblioteki kombinatoryczne i ich zastosowanie. Valentin Shick: Analysis of DNA and protein microchips. Chromatyna i białka jądrowe Anna Goc: Gen hydroksylazy tyrozynowej - okolica i sąsiedzi. Eliza Wyszko: Białka specyficznie wiążące DNA i RNA. Małgorzata Giel-Pietraszyk: Oddziaływanie peptydowych palców cynkowych z kwasami nukleinowymi. Ewa Markiewicz: Nadekspresja białka 14-3-3 w komórkach bakteryjnych i ziemniaku. Grzegorz Wilczyński: Technologia antysensu w badaniach fizjologicznej funkcji białek 14-3-3.

(II) Gliwice Scientific Meetings 1998 Structure and Function of the Genome 50 th Anniversary of Institute of Oncology in Gliwice 27-28.11.1998 Mathematical Models in Biology Jerzy Nakielski: Tensorial model of growth and cell divisions in the root apex Andrzej Polański: DNA statistics and the history of the population. Andrzej Świerniak Control of aminoacids concentration in cell populations as a potential technique of cancer cellspecific therapy. Chromatin Structure and Gene Expression Wolfgang Henning: Histone replacement variants. Andrzej Jerzmanowski: Chromatin structures in transcriptional regulation. Krzysztof Staroń: Eukaryotic topoisomerase I. Ryszard Rzepecki: Interactions of D. melanogaster karyoskeletal proteins - lamins and topoisomerase II with nucleic acids in vivo. Wolf H. Strätling: The nuclear protein ARBP/MeCP2. Jan Filipski: Nuclease hypersensitive sites and meiotic double-strand breaks in human DNA cloned in yeast. DNA Damage, Repair and Cellular Death Regen Drouin: UV induced DNA damage distribution at the DNA sequence level. Ryszard Oliński: Oxidatively damaged DNA bases - relevance to mutagenesis and cancer. Anna Kulma: Generation of transgenic potato plans differing in carbohydrate level by manipulation of 14-3-3 protein expression. Magdalena Milcarz: Apoptotic-like effect of 14-3-3 protein overexpression in E. coli. Piotr Widłak: DFF, human endonuclease activated during apoptosis. Genetic Polymorphism and Cancer Jerzy Ihnatowicz: The quantitative analysis of cancer epidemiology problems. Barbara Jarząb: Mutations of protooncogene RET and medullary thyroid carcinoma. Marek Rusin: Polymorphism of DNA repair genes. Maria Wideł: Individual radiosensitivity and DNA damage.

(III) Gliwickie Spotkania Naukowe 1999 Struktura i funkcje genomu 26-27.11.1999 Uszkodzenia i naprawa DNA: Mechanizmy Małgorzata Zdzienicka: Radiowrażliwość a naprawa dwuniciowych pęknięć DNA. Ryszard Oliński: Indukcja i reperacje oksydacyjnych uszkodzeń DNA. Marcin Kruszewski: Liczba wywoływanych przez H 2 O 2 uszkodzeń DNA zależy od poziomu wolnych jonów żelaza. Wanda Baer-Dubowska: Addukty policyklicznych węglowodorów aromatycznych z DNA i ich modyfikacja przez potencjalne czynniki chemoprewencyjne. Barbara Tudek: Lokalizacja cyklicznych adduktów zasad DNA w obrębie ludzkiego genu p53. Krzysztof Szyfter: Charakterystyka zmian liczby kopii DNA na poziomie chromosomowym w guzach pierwotnych i przerzutach w płaskonabłonkowym raku krtani. Maria Grąziewicz: Fapy-adenina; wpływ oksydacyjnej pochodnej adeniny na replikację DNA i jej właściwości mutagenne. Joanna Rzeszowska-Wolny: Białka rozpoznające uszkodzony DNA. Dorota Butkiewicz: Polimorfizm genów NER i ryzyko zachorowania na niedrobnokomórkowego raka płuc. Maria Wideł: Uszkodzenia DNA indukowane promieniami jonizującymi w limfocytach chorych na raka szyjki macicy i nowotwory głowy i szyi. Ryszard Rzepecki: Regulacja aktywności topoizomerazy II i jej wiązanie do kwasów nukleinowych podczas cyklu komórkowego. Bogdan Smołka: Metoda kometkowa; nowy sposób analizy obrazu. Zastosowanie biologii molekularnej w medycynie Jan Lubiński: Stan obecny i perspektywy diagnostyki molekularnej w medycynie. Włodzimierz Krzyżosiak: Strategie wykrywania mutacji w genach. Marek Mirowski: Zastosowanie mikroprocesorów genetycznych w diagnostyce raka tarczycy. Janusz Limon: Znaczenie techniki FISH w diagnostyce białaczek oraz litych guzów nowotworowych człowieka. Barbara Jarząb: Onkogen RET; znaczenie w patogenezie i diagnostyce raka tarczycy. Uszkodzenia i naprawa DNA: Efekty biologiczne Marek Gniazdowski: Leki przeciwnowotworowe a czynniki transkrypcyjne. Andrzej Pawlak: Genetyczna podatność na raka płuca i związane z nim mutacje somatyczne. Marek Rusin: Nowe polimorfizmy genów naprawy DNA-MGMT i MPG. Antonina Cebulska-Wasilewska: Porównanie uszkodzeń DNA i chromosomowych oraz podatność na promieniowanie UV i X w limfocytach ludzi zdrowych i pacjentów z nowotworem skóry.

(IV) Gliwickie Spotkania Naukowe 2000 Współczesna terapia nowotworów: od badań molekularnych do zastosowań klinicznych 24-25.11.2000 Biologia komórek nowotworowych Kazimierz Dux: Biologia nowotworów. Mieczysław Chorąży: Genetyka nowotworów - udział genów w nowotworzeniu. Jan Steffen: Dziedziczne predyspozycje do rozwoju nowotworu. Wenancjusz Domagała: Biologia komórki nowotworowej: czym różni się komórka nowotworowa od prawidłowej? Przemysław Janik: Angiogeneza w nowotworach. Czesław Radzikowski: Powstawanie przerzutów. Uszkodzenia i śmierć komórki Józefa Wesierska-Gadek: Role of poly (ADP - ribose) polymerase-1 in the regulation of p35 response to genotoxic stimuli. Ryszard Oliński: Analiza zawartości 8-okso-deoksyguanozyny i 8-okso-guaniny w moczu człowieka; czy ich poziom odzwierciedla aktywność enzymów reperacyjnych? Ewa Sikora: Kurkumina jako czynnik indukujący nietypową apoptozę komórek prawidłowych i nowotworowych. Andrzej Pawlak: Wzajemne oddziaływania niedotlenienia i ekspozycji na policykliczne węglowodory aromatyczne. Barbara Jarząb: Analiza ekspresji genu tyreoglobuliny: zastosowanie w monitorowaniu chorych na raka tarczycy. Janusz Siedlecki: Rola 3 ' niekodującej części RNA w ekspresji genów. Piotr Widłak: Białka chromatyny rozpoznające uszkodzony DNA. Modele matematyczne w biologii i medycynie Marek Kimmel: Wczesna detekcja raka płuc w oparciu o tomografię komputerową i analizę biomarkerów. Andrzej Płucienniczak: Wykorzystanie zjawiska supresji PCR, czyli patelnie w biologii molekularnej. Krzysztof Fujarewicz: Klasyfikacja w oparciu o analizę ekspresji genów. Andrzej Polański: Analiza stabilności biliniowego modelu chemioterapii nowotworów uwzględniającego fazoczułość leków. Genome Structure and Regulation of Gene Expression Nicolai Sjakste: Two-directional transcription of the chicken alpha-globin gene domain. Jean-Marc Matter: Functional interactions between bhlh transcription factors regulate neural determination in the CNS. Wojciech Makałowski: Organizacja i ewolucja genomu człowieka.

(V) Gliwice Scientific Meetings 2001 Molecular Biology and Cancer Research 23-24.11.2001 Chromatin structure and function Ronald Hancock: Molecular crowding and assembly of nuclear compartments. Nocolais Sjakste: Proteasome role in pathology, first studies on proteasome gene polymorphism. Jan Filipski: Localization of the hot spots of recombination in segments of human DNA cloned in YACs. Jiri Fajkus: Chromatin structure of plant telomeres and subtelomeres. Cellular stress and death Irena Szumiel: The celluar response to DNA damage; the importance of being p35 positive. Maciej Żylicz: Role of the heat shock proteins in cell transformation. Ewa Nino: Oxidized low density lipoproteins in the process of atherosclerosis. Józefa Gadek-Wesierski: Inducion of apoptosis in human cervix carcinoma cells during therapy by cisplatin. Andrzej Pawlak: Mutations of aryl hydrocarbon responsive elements (AHRE) determine the tissue specific genotoxic consequences of PAH exposure. Tatiana Kałuża: Real - Time PCR. DNA damage and repair Jacques Nino: Mutation strategies. Ryszard Oliński: Oxidative stress and cancer development. Krzysztof Szyfter: A link between chromosome instability, DNA damage and repair capacity and cancer risk factor. Piotr Widłak: Nucleases engaged in cell death. Marek Rusin: DNA damage recognition protein XPA regulation of its expression and function. Dorota Dziadkowiec: DNA repair and mating type switching in Schizosaccharomyces pombe. Mathematical modelling of biological processes Marek Kimmel: SNP haplotypes and cancer. Bogdan Lesyng: Modelling of biomolecular systems and processes using microscopic and mezoscopic approaches. Mirosław Lachowicz: Mathematical modeling of non-local phenomena in tumor development. Krzysztof Fujarewicz: Improved classification of microarray gene expression data using support vector machine. Cezary Labuda: New trends in molecular diagnostics.

(VI) Gliwice Scientific Meetings 2002 22-23.11.2002 New Trends in Cancer Therapy Beata Utracka-Hutka: Chemotherapy - where are you going? Principles, new targets, challenges for the future. Jan Walewski: Therapy for lymphoma: current concepts and new approaches. Jerzy Konopa: Mechanisms of action as a basis for the development of new antitumor compounds. Maciej Siewiński: Inhibitorotherapy of cancer. Rafał Tarnawski: How molecular biology may improve outcome of radiation oncology interactions. Transgenic Organisms in Agrobiotechnology and Medicine Mieczysław Chorąży: Genetically modified organisms - introduction. Marcin Łukaszewicz: Transgenic plants overexpressing biologically active compounds. Agnieszka Sirko: The potential of transgenic plants for subunit vaccine production. Jerzy Jurka: Transposable elements: horizontal transfer and mechanisms of integration. Genomics in Medicine Helena Sztajer: Genomics and proteomics as a tools for analysis of phospholipid hydroperoxide glutathione peroxidase expression and transformation during spermatogenesis. Włodzimierz Krzyżosiak: Translational regulation of the BRCA1 gene. Marek Figlerowicz: Discovery of RNAi phenomenon - turning-point in functional genomics. Catharina Larsson: Positional cloning of tumor suppressor genes in parathyroid tumorigenesis. Patrick Gaudray: Deciphering Menin's interaction networks as a tool to tackle its biological role. Barbara Jarząb: Expression profiling by DNA microarray in endocrine - related cancer. DNA Repair, Radiobiology and Medicine Marcel Blaese: Role of cytoplasmic retinoic acid binding proteins CRABPI and II in regulating sensitivity of tumor cells to retinoids and ionizing radiation. Kai Rothkamm: Cell-cycle-dependent contribution of non-homologous end joining and homologous recombination to the repair of radiation-induced DNA doublestrand breaks in mammalian cells. Ingo Brammer: Individual radiosensitivity: molecular mechanisms and clinical impact. Elisabeth Ortmann: Modulation of radiation induced apoptosis by antioxidant vitamins. Antonina Cebulska-Wasilewska: Predictive assays - comparison between various biological end-point and various doses. Nadzeya Rabakon: Genetic efficiency of low-dose ionizing radiation in small mammals under chronic irradiation. Barbara Tudek: Long-chain adducts of fatty acids derivatives to DNA bases, mutations and repair. Krzysztof Szyfter: Phenotypic and genotypic indications for an impaired DNA repair capacity in laryngeal cancer subjects. Ryszard Oliński: Oxidative DNA damage and repair; insight from determination of 8-oxoguanine and 8-oxo-2'- deoxoguanosine in extracellular fluids. Grażyna Motykiewicz: DNA repair capacity in lymphoblasts from sisters discordant for breast cancer. Miscellanea Ludmila Drobot: Ruk adaptor proteins - structural and functional features. Wiesława Widłak: Why spermatogenic cells are sensitive to elevated temperature. The role of heat shock proteins. Dorota Rybaczek: Premature mitosis (PCC) a preserved ability of chromatin to replicate the DNA. Olgierd Unold: Towards DNA based computer the initial state. Sergey Razin: Chicken domain of alpha-globin genes: organization and regulation of globin genes expression.

(VII) Gliwice Scientific Meetings 2003 21-22.11.2003 Structure and Functions of the Genome Sergey Razin: Domain organization of human dystrophin gene. Jan Filipski: Mapping of the hot spots of recombination in human DNA cloned in S.cerevisiae. Elena Youdinkova: Organization of the chicken domain of alpha-globin genes. Vlada Philmonienko: Nuclear myosin I and actin are required for transcription of ribosomal genes. Maria Malanga: Poly(ADP-ribose) reactivates stalled DNA topoisomerase I: relevance to genomic stability and cancer therapy. Marek Gniazdowski: Covalent binding of amidine analogues of anthracyclines to DNA. Transgenic Organisms in Agrobiotechnology and Medicine - Centre of Excellence PAGEN Workshop on Modifications of commercially Valuable Plants Bernd Müller-Röber: Transcription factor function search: combining genomics and single-gene approaches to discover new regulatory networks in plant biology. Holger Hesse: Transgenic plants as a tool to improve sulfur amino acid content in plants. Urte Schlüter: Manipulation of flax for improved fibre extractability. Jan Szopa: Flax engineering for fiber improvement. Marcin Łukaszewicz: The antioxidant potential of transgenic plants. Jacek Hennig: Functional analysis of glub gene in Solanum tuberosum plants. Janusz Zimny: Transgenic crops in the world. Modern Trends in Diagnosis and Therapy of Cancer Beata Utracka-Hutka: Targeted therapy. Adam Maciejewski, Bogusław Mąka: Reconstructive surgery. Rafał Tarnawski: Radiosurgery. Brygida Białas: Real-time brachytherapy of prostate cancer. Barbara Jarząb: Expression profiles in papillary thyroid cancer analysed by DNA microarrays. Maciej Małecki, Przemysław Janik: Angiogenic gene therapy: a bicistronic strategy. Małgorzata Wierzbicka: Biological implications of failures in solid tumours treatment. DNA repair and their role in carcinogenesis Ryszard Oliński: The molecular links between oxidative damage to DNA and cancer. Marcin Kruszewski: Labile iron pool, oxidative DNA damage and carcinogenesis. Miroslav Chovanec: DNA double-strand break repair and its implication in cancer. Rosa Goncharova: Some aspects of applying antimutagens as anticarcinogens. Joanna Rzeszowska-Wolny: Nucleotide excision repair new role in oxidative damage repair? Marek Rusin: DNA repair genes; polymorphisms and risk of cancer. Mathematical Models of in Biology and Medicine Jacek Leluk: Wrong assumptions and misinterpretations in molecular biology, biochemistry and bioinformatics. Aleksander Masny, Andrzej Płucienniczak: PCR performed at low denaturation temperatures PCR melting. Joanna Polańska: Using Gaussian mixtures to infer structure in microarray data. Tomasz Magdziarz: Designing drugs by docking ligands into proteins - chemical problems and technical challenges. Marcin Pacholczyk: Analysis of differences in protein substitution patterns based on statistical tests. Satellite workshop: Cytogenetic Markers in Assessment of Human Exposure to Carcinogenic Substances Maria Sąsiadek: Chromosomal aberrations and cancer risk. Maria Dušinská: Assessment of biomarkers of exposure, effect and individual susceptibility in workers exposed to mineral fibres. Francesca Marcon, Riccardo Crebelli: Can current biomarkers be applied in the monitoring of low environmental exposures? Results from an investigation on traffic wardens of Rome city. Grażyna Motykiewicz: Application of cytogenetic markers in the polluted region of Upper Silesia. Elżbieta Skrzydlewska: Green tea in cancer prevention.

(VIII) Gliwice Scientific Meetings 2004 19-20.11.2004 Mathematical Models in Genomics and Cancer Biology Session supported by Apple IMC Poland SAD Michał Dąbrowski: Identification of potential cis-regulatory features associated with a mode of gene expression common to neuronal differentiation and hippocampal development. Krzysztof Fujarewicz: Identification of models of cell signaling pathways. Piotr Formanowicz: Isothermic sequencing by hybridisation. Krzysztof Simek: SVD as a tool for pattern discovery in gene expression data. Bogdan Smołka: Fast denoising of cdna microarray images. Structure and Function of the Genome Sergey Razin: The spatial organization of DNA in eukaryotic cell nuclei plays an important role in determining positions of recombination hot-spots. Jan Filipski: Epigenetic regulation of transcription and the origin of isochors. Piotr Widłak: The other face of histone H1. Vasyl F. Chekhun: New trends in experimental oncology in Ukraine. New concepts and methods Lise L. Hansen: PCR amplification of highly GC-rich templates. An efficient tool in the search for new prognostic markers in cancer. Janusz M. Bujnicki: Protein structure prediction by consensus fold recognition and assembly of fragments. Gabriel Wcisło: From molecular studies to clinical practice. An EGFR (epidermal growth factor receptor) story. DNA Repair Mechanisms and their Role in Carcinogenesis Antonina Cebulska-Wasilewska: Response to challenging dose of x-rays as biomarker of susceptibility in molecular epidemiology. Wolfgang Goedecke: The fate of DNA doublestrand breaks: aspects of mitotic and meiotic cells. Andrzej Wójcik: Do interindividual differences in lymphocyte chromosome radiosensitivity exist? Ulla Kasten-Pisula: Molecular mechanisms of the individual radiosensitivity: impact on DNA repair. Paweł Jałoszyński: Fidelity or survival? How unrepaired DNA is replicated when polymerases encounter problems. Barbara Tudek: Processing of lipid peroxidation-derived DNA adducts by repair enzymes and DNA polymerases. Miroslav Chovanec: Repair of DNA doublestrand breaks of different origin in Saccharomyces cerevisiae. Cellular Stress, Signaling Pathways and Cancer Session supported by Committee for Human Genetics and Molecular Pathology, PAS Maciej Żylicz: Hsp70 and MDM2 are important for the transcriptional activity of wild type p53. Joanna Rzeszowska-Wolny: Gene expression profiles and cellular stress. Svetlana Sidorenko: CD150-mediated signaling. Lyudmila Sidorik: The role of molecular chaperons in cancer. Jekaterina Erenpreisa: Expression of meiotic genes and phenotype by irradiated tumour cells. Functional Genomics in Medicine Session supported by State Committee for Scientific Research (Grant PBZ-KBN-040/PO4/2001) Barbara Jarząb: Genomic approach to thyroid cancer. Małgorzata Wiench: RET protooncogene and gene expression profile of thyroid cancer. Joanna Polańska: Applications of mixture models to gene expression profiles. Katarzyna Lisowska: Gene expression profiling in hereditary breast cancer; preliminary results. Michał Jarząb: From microarray data to the biological relevance.

(IX) Gliwice Scientific Meetings 2005 The 80 th Anniversary of Professor Mieczysław Chorąży 18-19.11.2005 Structure and Function of the Genome - Epigenetic Mechanisms William T. Garrard: Mechanisms of activation and silencing of the immunoglobulin kappa locus. Andrzej Jerzmanowski: Chromatin remodeling and linker histones in plant development. Sergey Razin: Assembly of nuclear matrix - bound protein complexes involved in non-homologous end joining is induced by inhibition of DNA topoisomerase II. Harry Sherthan: Satellite DNA, meiotic telomeres and chromosome evolution. Jan Barciszewski: Diagnosis and therapy of brain tumors. Response to Stress and Alterations of Genome and Transcriptome in Cellular Pathology Lise Lotte Hansen: Genomic instability of the HCP region in somatic breast cancer. Ryszard Oliński: Clinical significance of oxidative DNA damage. Krzysztof Szyfter: Progression of head and neck cancer studied by molecular cytogenetics. Stanisław Cebrat: The role of crossing-over in the computer simulated populations. Protein Sciences in Biology and Medicine Alfred Pingoud: Engineering of meganucleases. Janusz M. Bujnicki: Protein structure prediction by combination of fold-recognition and de novo holding. Jerzy Ostrowski: Strengths and limitations of microarray- and mass spectrometry-based methods in clinical research. Michał Dadlez: Application of mass spectrometry for the studies of proteomes. Krzysztof Puszyński: Logical analysis of proteomic data. Marcin Pacholczyk: Some algorithms of molecular docking. Therapeutic Strategies and Mathematical Models in Contemporary Oncology Pedro de Campos-Lima: New strategies in therapy of virus-caused tumors Marek Los: Apoptin - a novel, cancer-selective killer Andrzej Świerniak: Antiangiogenic therapy as a control problem Anna Marciniak-Czochra: A simple mathematical model for cell signaling in radiation experiment Piotr Czerski: Sekwencjonowanie i synteza DNA Sympozjum satelitarne: Nowe leki i strategie terapeutyczne we współczesnej onkologii Piotr Wysocki: Efekt przeciwnowotworowy kaptoprilu druga strona medalu. Elżbieta Pajtasz-Piasecka: Aktywność przeciwnowotworowa szczepionki na bazie komórek dendrytycznych transdukowanych genami mysiej IL-12 lub IL-2 u myszy z zaawansowanym nowotworem MC38. Dominika Nowis: Badanie mechanizmów niszczenia komórek nowotworowych przez terapię fotodynamiczną oraz próby potęgowania jej efektywności. Danuta Duś: Białka oporności wielolekowej w komórkach macierzystych krwi. Maciej Ugorski: Wykorzystanie RNAi do hamowania ekspresji glikozylotransferaz. Joanna Wietrzyk: Toksyczność nowych analogów witaminy D i ich aktywność in vitro w terapii kombinowanej z cytostatykami w modelu raka gardła. Katarzyna Szczaurska: Aktywność przeciwnowotworowa bakteriofagów w terapii skojarzonej z cytostatykami. Janusz Boratyński: Koniugaty metotreksat nośnik właściwości chemiczne i biologiczne. Aleksandra Rusin: Przeciwnowotworowe i przeciwzapalne właściwości nowych koniugatów niesteroidowych leków przeciwzapalnych i oligomerów 3- hydroksymaślanu. Tomasz Cichoń: Kombinacja cyklofosfamid z cytokinami indukowanymi przez sekwencje CpG DNA w hamowaniu wzrostu doświadczalnych przerzutów czerniaka B16(F10) w płucach myszy.

(X) Gliwice Scientific Meetings 2006 The 10 th Anniversary of Gliwice Scientific Meetings 17-18.11.2006 Cell Signaling and Responses to Stress Carmel Mothersill: Radiation induced bystander effects in vivo are they protective or destructive? Maciej Żylicz: Role of molecular chaperones in cell transformation. Anna von Mikecz: Quality control in the cell nucleus by the ubiquitin-proteasome system. Ryszard Oliński: Oxidative DNA damage; cause or consequence of cancer? Barbara Tudek: Modulation of oxidative DNA damage repair by oxidative stress and neoplastic transformation. Jolanta Barańska: Nucleotide receptors and their role in cellular signaling in glioma C6 cells. Joanna Rzeszowska-Wolny: Intercellular communication in X-irradiated cells and its influence on gene expression profiles. Jarosław Śmieja: What mathematical modeling can help with in analysis of signaling pathways? (Lessons from modeling of IFN- pathway). Cell Death and Aging Ding Xue: Coordination of apoptotic DNA degradation and cell corpse engulfment in C. elegans. Ewa Sikora: What if not apoptosis? Andrzej M. Składanowski: Too many ways to die: cell death-cell survival dilemma in cancer chemotherapy. Gregor Meiss: Structure-function relationships in DNA-fragmentation factor. Piotr Widłak: Does active DFF need regulation? (How many steps for regulation of apoptotic nucleases?) Modern Trends in Cancer Diagnostics and Therapy Barbara Jarząb: Cancer transcriptome: factors determining gene expression profiles. Marek Jakóbisiak: Prospects of cancer immunotherapy. Marek Los: Hijacking cell survival pathways to selectively kill cancer cells. Hanna Rokita: Immunotherapy of neuroblastoma with peptide vaccines based on molecular mimicry of GD2 gangliosides. Aleksander Sieroń: Zinc-dependent metalloproteases and their inhibitors in biology and diagnostics of cancer. Rafał Tarnawski: Modern radio-oncology. Frank Koltrowitz: The experimental power of MACSmolecular gene expression analysis products. Biotechnologia w Polsce perspektywy rozwoju i problemy dydaktyczne Technologia: Andrzej Pilc: Nowe leki antypsychotyczne Stanisław Bielecki: Możliwości zewnętrznego i wewnętrznego stosowania celulozy mikrobiologicznej w medycynie Andrzej Płócienniczak: Produkcja ludzkiego hormonu wzrostu Jan Szopa: Genetyczne modyfikacje roślin uprawnych Bernard Korzeniewski: Analiza kontroli metabolicznej a biotechnologia OLYMPUS Optical: FluoView 1000 nowa jakość w mikroskopii konfokalnej Edukacja: Jacek Leluk: Zdalne nauczanie wczoraj, dziś i jutro. Amalia Guzdek: Biotechnologia w Uniwersytecie Jagiellońskim - dekada nauczania. Andrzej C. Składanowski: Patologia molekularna - jak są nauczani studenci Międzyuczelnianego Wydziału Biotechnologii Uniwersytetu Gdańskiego i Akademii Medycznej w Gdańsku - analiza SWOT Perspektywy: Korneliusz Miksch: Rola biotechnologii w zrównoważonym rozwoju województwa śląskiego Ludwik Tomiałojć: Ekologiczne i ekonomiczne źródła obaw przed szybkim wprowadzaniem upraw GMO Mieczysław Chorąży: Modyfikacje genetyczne nadzieje i obawy

XI th Gliwice Scientific Meetings 2007 Molecular Biology and Bioinformatics in Cancer Diagnostics and Therapy 16-17.11.2007 Modeling and Synthetic Approaches in Drug Discovery Johann Gasteiger: Explorations into biochemical pathways. Beata Walczak: A start-to-end approach to the analysis of proteomic data. Jaroslaw Polanski: The design and discovery of HIV integrase inhibitors. Alicja Ratuszna: The new photosensitizers and their application in Photodynamic Therapy. Timothy Madden: An approach to drug development in an academic environment. Waldemar Priebe: Design and development of novel anticancer drugs for treatment of brain tumors. Bogdan Lesyng: Oncogenic JAK/STAT signalling pathways and design of JAKkinase inhibitors. Grzegorz Grynkiewicz: Sugars in new drug design a lesson from natural products with anticancer activity. Wiesław Szeja: Glycoconjugates. Development of a new biologically active compounds. New Trends in Cancer Diagnostics and Therapy Thoralf Christoffersen: Mechanisms integrating signalling from G protein-coupled receptors and EGF receptors in normal and malignant gastrointestinal cells. Dagny Sandness: Role of different prostanoid receptors in the growth-stimulatory effects of prostaglandins. Barbara Tudek: DNA repair in the pathology of lung and colon cancer. Carmel Mothersill: Harnessing low dose radiation responses for radiation protection. Colin Seymour: Natural products as radiation response modifiers. Raisa Smolyakova: Prognostic molecular biologic markers in breast cancer. Walter Mier: The potential of endoradiotherapy for the development of highly specific cytostatics. Dariusz Iżycki: Genetic antimelanoma vaccines - promises and obstacles. Marek Los: Targeted cancer therapies using derivates of natural products Brevinin-2R and Apoptin as examples. Maciej Giefing: Array-GCH based identification of oncogenes and tumor suppressor genes involved in laryngeal cancer. Maria Obolenskaya: Novel approach in the study of IFN alpha activity. Krzysztof Puszyński: Deterministic model of p53 Mdm2 signaling pathway. Ion Channels in Biology and Medicine Mustafa B. A. Djamgoz: Voltage-gated Na channel upregulation and potentiation of cellular behaviours in metastatic disease. Zbigniew Grzywna: Wound healing as a diffusional sorption process. Steven White: Making sense of voltage sensors. Jerzy Mozrzymas: Pharmacokinetic description of GABAergic current modulation by benzodiazepines in neurons. Maria Mycielska: Metabolic pathways in human prostate cancer cells: regulation by voltagegated Na channel activity. Krzysztof Dołowy: Ion channels and genetic disorders the cystic fibrosis case. Genomics and Proteomics in Medicine Adam Godzik: Metagenomics provides new perspectives on human health. Daria Handkiewicz-Junak: Molecular PET imaging and gene expression profiling of malignant tumors. Krzysztof Fujarewicz: Monte Carlo methods for genomic data analysis. Piotr Widłak: Mass Spectrometry analyses of the serum proteome - an important tool of clinical proteomics. Joanna Polańska: Application of the Gaussian mixture model to proteomic MALDI-ToF mass spectra. Tomasz Bieńkowski: Discovery and validation of biomarkers by Mass Spectrometry. Jacek Leluk: Theoretical background and utility of commonly used sequence multiple alignment tools. David Hulmes: Controlling the assembly of the cellular microenvironment and applications in tissue regeneration and repair. Aleksander Sieroń: Genetic engineering of ECM compounds for regenerative medicine. Marek Kowalczuk: Biopolyesters and their synthetic analogues of controlled structure at the molecular level for regenerative medicine. Anna Szydło: Copolymers of synthetic biodegradable scaffold with collagen type I. Ksymena Urbanek: Characterization of nonadherent rat bone marrow stem cells (VSEL cells).

XII th Gliwice Scientific Meetings 2008 21-22.11.2008 Responses to Ionizing Radiation and DNA Damage Kevin Prise: New insights on bystander signalling: The role of DNA damage sensing and repair. Carmel Mothersill: Bystander effects and adapative responses induced by radiation exposure. Marie Boyd: Bystander effects and targeted radiotherapy for gliomas. Joanna Rzeszowska-Wolny: Transcription profile change after irradiation or in bystander cells; differences between cell lines. Rachel Martin: Characterizing protein post translational modifications using MALDI mass spectrometry. Beata Walczak: Proteomics: automated electro-phoregram analysis. Chryso Kanthou: Response of the tumour vasculature to radiation and vascular disrupting agents. Walter Mier: The targeting of melanoma for endoradiotherapy. Micheline Giphart-Gassler: Towards a gene expression profile to classify patients for normal tissue toxicity. Molecular Channels Mustafa B.A. Djamgoz: Voltage-gated ion channels as mediators of growth factor effects in metastatic disease. Adam Szewczyk: Mitochondrial potassium channels. Maria Mycielska: Citrate transport in human prostate cancer cells: regulation by functional voltage-gated Na + channel expression. Krzysztof Dołowy: The role of mitochondrial ion channels in ischemic preconditioning. Systems Biology, Bioinformatics and Signaling Pathways Miguel Rubi: Somatic exocytosis of serotonin mediated by molecular motors. Jerzy Mozrzymas: Impact of acidosis on modulation of GABAergic IPSCs by benzodiazepine receptor agonists. Jerzy Jurka: Mobile DNA elements throughout evolution. Maria Obolenskaya: Folate-related metabolism in human placenta. Jan Poleszczuk: Tumor development model under angiogenic signaling with dependence on vessel impairment. New Drugs and Treatments Ryszard Oliński: Oxidative processes and cancer. Jean Francois Mouscadet: in silico study suggests that Raltegravir-resistant mutations modify the DNA recognition properties of HIV-1 integrase. Marek Los: Apoptin and its derivatives as molecular templates for the development of Bcr-Abl kinase inhibitors. Alexa Schieck: Identification of the determinant of hepatitis B virus liver tropism and its implications for hepatocyte-specific drug targeting. Martin Dolezal: Biologically active pyrazines, the past and the future. Experimental Biotechnology Wiesław Szeja: Synthetic glycomix for mining natural products as drug leads. Part I. Grzegorz Grynkiewicz: Synthetic glycomix for mining natural products as drug leads. Part II. Aleksandra Rusin: Genistein derivatives and their biological activity. Krystiana Krzysko: Binding of genisteine derivatives to abl and lck protein kinases, and to microtubules - modelling studies. Andrzej Gamian: Glycation of proteins as their modification in physiology and disease. Olena Palyvoda: Molecular organization in self-assembled monolayers used for neuronal cell growth. Joanna Polańska: Statistical processing of DNA microarray data - detecting subtle changes of gene expressions.

XIII th Gliwice Scientific Meetings 2009 20-21.11.2009 2 nd Polish-German Cancer Workshop Molecular Epidemiology of Cancer Kari Hemminki: Genetic basis of familial aggregation of cancer. Jan Lubiński: The latest advances in clinical genetics of tumors including gastric cancer. Ute Hamann: Search for modifiers of hereditary breast cancer risk. Asta Försti: Evidence for genetic basis in breast cancer survival. Ewa Grzybowska: Molecular epidemiology of hereditary breast and ovary cancer in Silesia, clinical course of breast and ovary cancer in respect to polymorphisms of PGR and MDR1 genes. Annekatrin Lukanova: Pregnancy hormones and maternal cancer. Dorota Butkiewicz: Genetic influences on survival in lung cancer. Federico Canzian: Genome-wide studies in cancer. Krzysztof Szyfter: Identification of laryngeal cancer-related genes using high resolution array-cgh technique. Functional Genomics in Cancer Research Stefan Wiemann: Modeling and testing of cell cycle regulation via the ErbB protein and mirna network in breast cancer. Aurelio Teleman: Identification of a phosphatase regulating insulin signaling. Marcin Szaumkessel: Pyrosequencing-based DNA methylation profiling of Fanconi anemia/brca pathway genes in head and neck squamous cell carcinoma. Sandra Steinbrink: Genome-wide functional screens to identify novel factors in cancer pathways. Joanna Polańska: New mathematical approaches in analyses of genomic and proteomic data. Barbara Jarząb: Thyroid carcinoma as a model for gene expression profiling of cancer. Jörg Hoheisel: Functional genomics and proteomics in pancreatic cancer research. Jolanta Kupryjańczyk: Prognostic and predictive factors in ovarian cancer results of verification of DNA microarray data. Magdalena Skrzypczak, Jerzy Ostrowski: Potential and challenges of microarray data analyses for predicting oncogenic signaling in colon tumors. Anna Fiszer-Kierzkowska: Molecular profiling of histopatologically normal prostate tissue adjacent to cancer. Piotr Widłak: MALDI-TOF MS-based serum proteome pattern analysis in molecular diagnostics of breast cancer. Molecular Biology, Biotechnology and Bioinformatics in Cancer Diagnostics and Therapy. Bystander Mechanisms as Targets for Cancer Radiotherapy Carmel Mothersill: Targeting bystander signalling and response pathways for cancer drug development. Marie Boyd: Bystander effects elicited by different radiation qualities - therapeutic opportunities? Elisabeth Schueltke: Synchrotron radiotherapy for human glioma: role of bystander mechanisms. Mansoor Ahmed: High-dose lattice radiation therapy: clinical, physics and biological perspective of bystander effects. Wojciech Jurczak: Haematologic toxicity of radioimmunotherapy.colin Seymour: Radiation-induced bystander effects in vivo: possible novel targets. James Murphy: Low LET radiation and bystander factor damage to mammalian mitochondria. Bruce C. McKay: Targeting transcriptioncoupled repair as an anti-cancer strategy. Anna Marciniak-Czochra: Characterization of the hematopoietic stem cells using mathematical models. Krzysztof Puszyński: Crosstalk between p53 and nuclear factor-kappab systems: proand anti-apoptotic functions of NF-kB. Joanna Rzeszowska-Wolny: Blood cells, can they be important in bystander effects? Ion Channels and Cancer Miquel Rubi: A thermodynamic description of active transport through channel proteins. Walter Stühmer: A potassium channel involved in cancer. Maria Mycielska: Cloning and characterization of citrate transporter and its K regulatory component in prostate and prostate cancer.

XIV th Gliwice Scientific Meetings 2010 26-27.11.2010 Stress Response Mechanisms and Their Usefulness in Prediction of Cancer Response to Therapy Luciene Zanchetta: Simulated sunlight-induced damage to mitochondria and mtdna in human skin cells. Geza Sáfrány: Low dose radiation induced transcriptional alterations in bystander primary human fibroblast cells. Carmel Mothersill: Issues in the interpretation of low dose effects in radiobiology and environmental radiation protection. Colin Seymour: Update on communication of bystander signals between organisms. Rob Mairs: Potent bystander effects are induced by targeted radionuclides. Joanna Rzeszowska-Wolny: Oxidative stress and bystander effect. Lyudmila Drobot: The oncogenic potential of adaptor protein Ruk/CIN85 in human breast adenocarcinoma. Mateusz Gałuszka: CLC bio-specialized software solutions for genetics and genomics. William Amos: Exploring patterns of nonrandomness in human mutations. Olivier Lichtarge: Evolution: a guide to protein function and its redesign. Marek Kimmel: Patterns of evolution of human genetic disease with implications for deep sequencing methods. New Drugs and Treatments Ross Hannan: Transcription by RNA polymerase I as target for anticancer therapy. Wiesław Szeja: Synthesis and biological activity of genistein glycosides and glycoconjugates. Ilona Wandzik: Synthesis of complex derivatives of uridine as potential inhibitors of glycosyltransferases. Aleksandra Rusin: Biological activities of synthetic genistein derivatives. Molecular Modeling and Bioinformatics Tools Andrzej Polanski: Large scale searching for exact tandem repeats in genomes based on the Burrows - Wheeler transform algorithm. Krzysztof Fujarewicz: Genomic data analysis with bootstrapping. Jacek Koronacki: A reliable and simple approach to feature selection and interdependency discovery in supervised classification.

XV th Gliwice Scientific Meetings 2011 18-19.11.2011 Mechanisms of Metastasis session co-organized by EACR members Claudine Kieda: Tumour angiogenesis normalization in the prevention of metastasis. Angels Sierra: Brain metastasis proteins and their interactions: a rational predictive biomarkers research. Ingeborg Tinhofer: Incidence and prognostic role of circulating tumor cells in squamous cell carcinoma of the head and neck region. Lyudmila B. Drobot: The biological role of adaptor/scaffold protein ruk/cin85 in breast carcinogenesis. Marek Los: Attempts to target cancer stem cells. Salinomycin as an example. Maciej Ugorski: The role of ceramide galactosy-ceramide (UGT8), a new molecular marker of breast cancer malignancy, in cancer progression. Regulation of Gene Expression at the Transcript Level Martin Simard: Understanding RNA silencing pathways through the Argonaute proteins. Gunter Meister: Analysis of Argonaute interactions in mammalian cells. Petr Svoboda: Unique regulation of small RNAs during oocyte-to-embryo transition in mammals. Anna Kurzyńska-Kokorniak, Marek Figlerowicz: Modulation of microrna biogenesis by using short oligo-rna molecules. Krystian Jażdżewski: The role of microrna sequence variation in thyroid cancer. Witold Konopka: Hypothalamic mirna suppresses obesity in mice. Ana Kozomara: The mirbase and the deepsequencing data. Kathrin Leppek: Roquin promotes rapid TNF mrna degradation via a stem-loop recognition element. Joanna Rzeszowska-Wolny: MicroRNA and RNA oxidative damage. Genes and Response to Radiation: Low Doses, Bystander Effects Carmel Mothersill: Emerging issues in radiobiology the impact of non-targeted effects. Marek K. Janiak: Antineoplastic effects of lowlevel exposures to ionizing radiation. Marek Kimmel: Spatial and stochastic effects in models of cell interaction Andrzej Świerniak: Bystander effect modeling using evolutionary games. Tomasz Wojdyła: Investigating the genealogical relationship among Slavs, Balts and Finns using demographic network model. Maria Wideł: Protective bystander effect. Piotr Widłak: Radiation-related changes in serum proteome profiles detected by MS in blood of patients treated with RT due to larynx cancer. Colin Seymour: The Ego, The Id, and Radiotherapy. Polish-German-American Workshop on Progress in Neurooncology: From the Bench to the Clinic Brain tumours biology Bożena Kamińska-Kaczmarek: Glioma initiating cells and immune microenvironment of gliomas. Marcel Kool: Integrated genomics on molecular subtypes in medulloblastoma. Stanisław Szala: Tumor vasculature in malignant gliomas. Frank Winkler: New insights into brain tumor biology by intravital microscopy. Klaus-Rudiger Trott: Why gliomas are radioresistant? Amir Abdollahi: Next Generation NeuroRadioOncology. Diagnostics and Therapy David Capper: Visualizing mutations: application of IDH1 and BRAF mutation specific antibodies in neuropathology. Barbara Bobek-Billewicz: Brain tumor properties to be identified by MRI - not always a success story. Henryk Majchrzak: Progress in surgical treatment of low grade gliomas. Pawel Nauman: Different aspects of surgery for primary brain tumours. Volker Budach: Radiosurgery and fractionated radiotherapy of benign brain tumours. Rafał Tarnawski: Prophylactic cranial irradiation with dose reduction in regions of active neurogennesis - a pilot study for SCLC patients with metastases in brain. Novel Therapeutic Modalities Volker Budach: Nano-Thermo-Radiotherapy or recurrent gliomas results of a new therapeutic modality. Timothy Madden: Translating innovative therapies for CNS malignancies - overcoming impediments. Charles Conrad: Oncolytic adenovirus therapy for brain tumors: a guide for development from the bench to the bedside in the academic setting. Waldemar Priebe: Discovery and development of novel therapies for brain cancer.

XVI th Gliwice Scientific Meetings 2012 16-17.11.2012 Structure of the Nucleus and Regulation of Gene Expression Jan Brzeski: Maize in the maze: a rough guide to the puzzling epigenetics of paramutation. Sergey Razin: Folded chromatin domain instead of an active chromatin hub: a model based on reconsidered essentials of the chromosome conformation capture procedure. Sławomir Kumala: The influence of chromatin topology on the accessibility of DNA to damage. Ronald Hancock: New models of the nucleus and chromosomes. Cellular Responses to Ionizing Radiation and Stressing Factors session co-organized by EACR members Mary Helen Barcellos-Hoff: Microenvironment matters: contributions to radiation carcinogenesis. Carmel Mothersill: Transmission of signals from irradiated rats to cage mates: an inter-animal bystander effect. Colin Seymour: The first cut is the deepest. Barbara Tudek: Repair of oxidative DNA damage during development of colon cancer. Selectively Cytotoxic Proteins Mathieu H. Noteborn: Apoptin induces cell death by targeting various tumor processes. Mahvash Tavassoli: Human Gyrovirus Apoptin shows a similar function to VP3/Apoptin. Stian Knappskog: Inactivation of the TP53 gene or the p53 regulators Chk2 / ATM predicts resistance to anthracyclines in breast cancer. Marek Los: Modeling of interaction between BCR-ABL and apoptin - novel way for argeting the deregulated Abelson kinase activity. Proteomics session co-organized by Polish Society of Proteomics Andreas Rőmpp: High resolution mass spectrometry imaging comprehensive and specific histological information at cellular resolution. Jacek R. Wiśniewski: Quantitative study of colorectal cancer to a depth of 10,000 proteins using laser microdissected formalin fixed and paraffin embedded tissue. Marcus Macht: Proteomics through integrated MALDI and ESI. Jerzy Silberring: Rapid analysis of drugs of abuse as an initial step towards predictive toxicology. Łukasz Marczak: Mass spectrometry based analysis of protein N-homocysteinylation. Joanna Polańska: Detection and quantification of MALDI ToF spectral peaks by using Gaussian mixture decomposition. Piotr Widłak: Mass profiling of cancer serum proteome - does it provide any useful information? Systems Biology Mieczysław Chorąży: The systems biology: introductory remarks. Izabela Makałowska: Retrogenes trash or treasure? Marek Rusin: Cross-talk between p53 and Akt kinase pathways. Joanna Janiszewska: micrornas and their importance in laryngeal carcinoma. Marek Kimmel: Variability and homeostasis in cycling cell populations. Andrzej Świerniak: Extended model of interaction between tumour cells.

XVII th Gliwice Scientific Meetings 2013 15-16.11.2013 Regulation of Gene Expression and Replication Anke van den Berg: The role of micrornas in B cell Hodgkin and non-hodgkin lymphoma. Joost Kluiver: Long noncoding (lnc)rnas: novel players in B-cell lymphoma. Małgorzata Czyż: Heterogeneity of melanospheres: therapeutic implications. Krzysztof Puszyński: Dynamics of intracellular processes. Cellular Pathways Driven by Reactive Oxygen Species Sebastian Student: Reactive oxygen species in the nucleus and cell death. Carmel Mothersill: Radiation-induced nontargeted effects: horizontal and vertical transmission of genetic change mediated by oxidative stress? Barbara Tudek: Lipid peroxidation modulates DNA repair and sensitizes cells to genotoxic factors. Natasha Kopitar: Deletion of stefin B gene enhances mitochondrial ROS formation and Nlrp3 inflammasome activation. DNA Repair in Aging and Cancerogenesis Leon H Mullenders: Spot on the DNA damage response: from lesion recognition to human disease and therapy. Wojciech Niedźwiedź: BLM collaborates with TOPBP1 in promoting checkpoint activation and replication fork stability. Miroslav Pirsel: DNA repair helicase the story with an unexpected end. Grażyna Mosieniak: DNA damage response in cancer cell senescence. Cancer Proteomics and Metabolomics session co-organized by Polish Society of Proteomics Corinna Henkel: MALDI imaging in clinical research: searching for the Holy Grail. Angels Sierra: Proteins and protein-protein interacting motifs to therapeutic target of metastasis. Tone F. Bathen: Metabolic profiling of breast cancer. André Goffeau: Targeting selectively the unique energy metabolism of cancer with a small molecule inhibitor. Andrzej Swinarew: The instrumental analysis of novel polymeric materials for bioapplications. Dietary Factors in Cancer Prevention session co-organized by EACR members Wanda Baer-Dubowska: Diet and cancer: from epidemiological data to mechanism-based cancer prevention. Adriana Albini: The tumor microenvironment as target for cancer therapy and prevention by dietary components. Karen Brown: Development of resveratrol for cancer chemoprevention. Albena Dinkova-Kostova: Chemoprevention against cancer by isothiocyanates. Jędrzej Antosiewicz: Chemoprevention of prostate cancer by organosulfur compounds from garlic. Wim Van den Berghe: Promises & challenges in epigenetic remodeling of breast cancer metastasis by natural withanolides from Withania somnifera (Ashwagandha). Agnieszka Bartoszek: Discoveries of experimental chemoprevention - how to exploit them in rational design of health quality and therapeutic foods. Cancer Killing Sun Xiao-Feng: Biomarkers in colorectal cancer. Marek Los: Salinomycin experimental drug with preferred toxicity towards cancer stem cells, the role of autophagy in salinomycin toxicity. Nikolaos Sfakianakis: Numerical study of cancer invasion of extracellular matrix. Katrina Erenpreisa: Senescence, polyploidy, and stemness three components of the response of tumour cells to DNA damage. Kourosh Lotfi: P-glycoprotein transport of the active imatinib metabolite, CGP- 74588, in chronic myeloid leukemia cells. Jerzy Pieczykolan: Evaluation of novel, anticancer, targeted fusion biomolecule with high antiangiogenic and cytotoxic activity summary of preclinical findings.

XVIII th Gliwice Scientific Meetings 2014 21-22.11.2014 Transcriptional Responses to Stress Allan R. Brasier: NF-kB signaling and the innate immune response. Neil D. Perkins: Regulation of cancer cell proliferation and survival by NF-kB. Bożena Kamińska: Transcriptional and epigenetic mechanisms controlling inflammation. Marek Kimmel: Simplicity and complexity in models of cell signaling. Tomasz Lipniacki: NF-kB and IRF3 crosstalk signaling in MEFs. Mariusz Hartman: Immediate and long-term molecular response of melanoma cells to changes in microenvironment. Biomaterials and Nanomedicine Mehrdad Rafat: Bioengineered collagen constructs for cell-based regeneration of the cornea. Katerina Chlichlia: Magnetic and biogenic nanoparticles for cancer therapy. Ramunas Valiokas: Biopatterning techniques in tissue engineering. Łukasz Zarodkiewicz: AFM-IR: Combining atomic force microscopy and infrared spectroscopy for multifunctional measurements nanoscale chemical characterization. Glycobiology in Medicine Anna Lityńska: The role of aberrant glycosylation in human melanoma progression to more malignant phenotype. Marcin Czerwiński: Glycosyltranferases and blood group antigens. Wojciech Jachymek: Bacterial glycomics: new approach to vaccine production. Yanusz Wegrowski: Matrix proteoglycans as regulators of tumor progression. Bioinformatics and Regulatory Mechanisms session co-organized by EACR members Till Bretschneider: Image-based modeling of cell motility. Sascha Ott: Analysis of DNase-seq data. Franck Delaunay: Multispectral fluorescent single live cell imaging to analyse the cell cycle and the circadian clock dynamics. Carmel Mothersill: Radiation-induced bystander signals: evidence for a role of secondary UVA emission in the generation of oxidative stress and bystander effects by beta irradiation of human keratinocytes. Piotr Formanowicz: Petri net based approach for modeling and analysis of selected aspects of atherosclerosis. Krzysztof Kucharczyk: Minor genetic variants discovery and detection down to 0,1% level at the heterogenic tumor material by the MSSCP method. Michal Braczkowski: Application of ROCHE Diagnostics products for gene expression studies. Satellite Workshop: Genes Environment Interactions Maria Dusińska: Challenges with geneenvironment interactions: Where we are and where we need to go? Sofia Pavanello: Monitoring of exposures to carcinogens: Does the procedure need a rethink? Karin Broberg-Palmgren: Epigenetics of metals. Natalia Pawlas: Genetic susceptibility to metals. Süreyya Meriç Pagano: Multi-bioassay toxicity evaluation of a mixture of different group of pharmaceuticals. Norbert Kreuzinger: Wastewater treatment plants as a hub between clinical and environmental antibiotic resistance. Aneta Łuczkiewicz: Human-associated bacteria and their mobile genetic elements - important minority in wastewater and wastewater impacted ecosystems. Aleksandra Ziembińska-Buczyńska: Antibiotics and their resistance genes in the environment bacterial opportunity or threat?

XIX th Gliwice Scientific Meetings 2015 20-21.11.2015 Intra-Tumor Heterogeneity and Evolution session co-organized by EACR members Urszula Hibner: Cancer and evolution. Anna Golebiewska: Clonal evolution meets cancer stem cells: in-depth analysis of genetic and phenotypic heterogeneity in glioblastoma. Gareth Wilson: Deciphering cancer genome evolution and intra-tumour heterogeneity. Trevor Graham: Intra-tumour heterogeneity as a pan-cancer prognostic biomarker. Bożena Kamińska-Kaczmarek: Cancer stem cells and immune microenvironment. Anke van den Berg: Genomic inter- and intratumor heterogeneity in primary lung cancer and its metastasis. Kathrina Erenpreisa: Sub-cellular heterogeneity and asymmetry in fate choice of irradiated HeLa and etoposide-treated ovarian teratocarcinoma PA1 cells. Marek Los: Generation of limbal epithelial cell progenitors by two methods: by differentiation from ips cells and by direct transdifferentiation from human dermal fibroblasts. Radiation Biology Serge Candeias: Effects of low dose radiation on the T lymphocyte repertoire in the mouse: analysis from a TCR point of view Ingeborg Tinhofer-Keilholz: Mutational profiling using next-generation sequencing reveals distinct molecular mechanisms of radioresistance in HPV+ and HPV- head and neck cancer. Piotr Widłak: Signature of serum proteome in patients exposed to ionizing radiation. Karol Jelonek: Characterization of exosomes released from irradiated cells. Andrzej Swinarew: MALDI-ToF and UHPLC in peptide and protein characterization - potential application in radiation research. Klaus H. Maier-Hein: Data-driven oncologic image analysis. David P. Kreil: Power and limitations of RNA- Seq: findings from the SEQC consortium. Roles of Noncoding RNAs Gunter Meister: RNA-binding proteins as regulators of coding and non-coding gene expression. Joanna Rzeszowska-Wolny: X-ray induced changes in RNA interference suggest independent modulation of mrna and protein levels. Joost Kluiver: Non-coding RNAs as oncogenic components of the MYC regulatory network in Burkitt lymphoma. Gabor Szabo: DNA/RNA hybrids in the chromatin. Mitochondrial Channels and Reactive Oxygen Species Adam Szewczyk: What we don't know about mitochondrial potassium channels. Krzysztof Dołowy: Ion channels in mitochondria: the matter of life and death. Piotr Bednarczyk: Regulation of mitochondrial potassium channels. Przemysław Borys: Estimation of the maximum flux through ion channel. Magdalena Skonieczna: Inhibition of the voltagedependent anion channels and their influence on cell functioning. Jakub Hanus: Induction of necroptosis by oxidative stress in retinal pigment epithelial cells. Katarzyna Szołtysek: Role of reactive oxygen species in crosstalk between UV and cytokine activated signaling. Szymon Borek: Modification in modern tools for cell based assays including mitochondria and reactive oxygen species analysis. Bioinformatics Jacek Koronacki: Discovering interdependencies of features in disease-related genomic data. Jan Komorowski: Genes causing many cancers are located near tumor-mutated motifs for the CTCF and other transcription factors. Marek Kimmel: Modeling lung cancer drivers based on the cancer genome atlas data.

XX th Gliwice Scientific Meetings 2016 18-19.11.2016 Crosstalk between the Heat Shock Response and Cancer Gabrielle Multhoff: Heat shock response and NK mediated immunity in cancer therapy. Lea Sistonen: Transcriptional re-programming of genes in cell stress and cancer - synergistic and opposite effects of heat shock factors, HSFs Michael Y. Sherman: Targeting Hsp70 in cancer. Maciej Żylicz: Chaperone mediated cancer cell chemoresistance. Wiesława Widłak: HSF1 contribution to cancer cell phenotype. Dorota Ścieglińska: HSPA2 - cytoprotective or regulatory protein? Molecular and Numerical Gears of Circadian Clocks Hans Reinke: Crosstalk of stress response pathways and the circadian clock in mammals. ncis Lévi: Personalising cancer treatments through systems chronotherapeutics. Elham Farshaid: The circadian clock proteins BMAL1 and CLOCKcontrol G2/M cell cycle transition. Celine Feillet: The circadian clock-cell cycle connection. Joanna Rzeszowska-Wolny: Reactive oxygen species and circadian rhythms. Krzysztof Psium-Maksymowicz: Platform for remote testing and analyzing of biomedical data. Marek Zurawski: Microscale thermophoresis: quantitative interaction analysis and beyond. Regulatory RNA Angel Barco: Interplay of transcriptional and epigenetic mechanisms in neuronal activitydriven gene expression. Włodzimierz Krzyżosiak: Small RNAs in Triplet Repeat Diseases. (25 ) Krzysztof Chylinski: Sharpening the knives of CRISPR/Cas9. Marek Los: MicroRNAs, regulators of cell proliferation and (cancer) cell stemless - mir- 301a as an example. Krzysztof Fujarewicz: A model for the effects of ionizing radiation on microrna-mediated regulation of mrna levels in cells. Witold Konopka: Neuronal RNA processing in memory formation. Biomaterials and Medical Biotechnology Mehrdad Rafat: Artificial corneas, clinical trials - example of a successful bioengineering of an organ. Judith Staerk: Lamin B1-mediated gene regulation during human hematopoiesis. Emilia Wiechec: Rate-limiting energy enzyme in carbohydrate metabolism PFKFB3 - differential expression inips and in cancer stem cells. Jacek Kubiak: Preventive measures against chronic rejection of heart transplants. Anna Mielańczyk: Polymethacrylates as drug carriers - structure vs cell viability in MCF-7 cell lines. Chromatin Structure and Modulation of Transcription session co-organized by EACR members Marcelo Alda: WWOX, the FRA16D chromosomal fragile site gene, at the crossroads of cancer and CNS pathology. Rami Aqeilan: Role of tumour suppressor WWOX, the gene product of common fragile site FRA16D, in human diseases. Andrzej Bednarek: The role of Notch signaling pathway in regulation of gene expression in cancer. Sergey Razin: Self-organization of a chromatin fiber.

Lecturers that contributed to Gliwice Scientific Meetings in years 1997-2016 Abdollahi, Amir German Cancer Research Center, Heidelberg Albini, Adriana IRCCS MutiMedica, Milan Aldaz, Marcelo University of Texas, MD Anderson Cancer Center, Houston Amos, William Cambridge University, Cambridge Antosiewicz, Jędrzej Medical University of Gdansk, Gdańsk Aqeilan, Rami Hebrew University, Jerusalem Baer-Dubowska, Wanda Poznan University of Medical Sciences, Poznań Barańska, Jolanta Marceli Nencki Institute of Experimental Biology, PAS, Warszawa Barcellos-Hoff, Mary Helen New York University School of Medicine, New York Barciszewski, Jan Institute of Bioorganic Chemistry, PAS, Poznań Barco, Angel Miguel Hernandez University, Alicante Bartnik, Ewa University of Warsaw, Warszawa Bartoszek, Agnieszka Medical University of Gdansk, Gdańsk Bathen, Tone F. Norwegian University of Science and Technology, Trondheim Bednarczyk, Piotr Warsaw University of Life Sciences, Warszawa Bednarek, Andrzej Medical University of Lodz, Łódź Bielecki Stanisław Technical University of Lodz, Łódź Blaese, Marcel University of Tubingen, Tubingen Bobek-Billewicz, Barbara MSC Cancer Center and Institute of Oncology, Gliwice Borys, Przemysław Silesian University of Technology, Gliwice Boyd, Marie Cancer Research UK, Glasgow Brammer, Ingo University of Hamburg, Hamburg Brasier, Allan R. University of Texas, Medical Branch, Galveston Bretschneider, Till Warwick Systems Biology Centre, Coventry Broberg-Palmgren, Karin Karolinska Institutet, Lund Brown, Karen University of Leicester, Leicester Brzeski, Jan Copernicus Science Center, Warszawa Budach, Volker Charite University, Berlin Bujnicki, Janusz M. International Institute of Molecular and Cellular Biology, Warszawa Butkiewicz, Dorota MSC Cancer Center and Institute of Oncology, Gliwice Campos-Lima, Pedro Laval University, Quebec Candeias, Serge CEA, Grenoble Canzian, Federico German Cancer Research Center, Heidelberg Capper, David German Cancer Research Center, Heidelberg Cebrat, Stanisław University of Wroclaw, Wrocław Cebulska-Wasilewska, Antonina Institute of Nuclear Physics, PAS, Kraków Chekhun, Vasyl F. Institute of Experimental Pathology and Oncology, Kiev Chlichlia, Katerina Democritus University of Thrace, Alexandroupolis Chorąży, Mieczysław MSC Cancer Center and Institute of Oncology, Gliwice Chovanec, Miroslaw Cancer Research Institute, Bratislava Christoffersen, Thoralf University of Oslo, Oslo Chyliński, Krzysztof CRISP-Lab, VBCF ProTech, Vienna Conrad, Charles University of Texas, MD Anderson Cancer Center, Houston Crebelli Riccardo Istituto Supriore di Sanita, Rome

Czerwiński, Marcin Czyż, Małgorzata Dadlez, Michał Dąbrowski, Michał Delaunay, Franck Dinkova-Kostova, Albena Djamgoz, Mustafa B.A. Dolezal Martin Dołowy, Krzysztof Domagala, Wenancjusz Drobot, Ludmila B. Drouin, Regen Dusińska, Maria Dux, Kazimierz Dziadkowiec, Dorota Erenpreisa, Katrina Fajkus, Jiri Figlerowicz, Marek Filipski, Jan Fiszer-Kierzkowska, Anna Farshaid, Elham Feillet, Celine Formanowicz, Piotr Försti, Asta Fujarewicz, Krzysztof Gamian Andrzej Garrard, William T. Gasteiger, Johann Gaudray, Patrick Getto Philippe Giefing, Maciej Giel-Pietraszyk, Małgorzata Giphart-Gassler, Micheline Gniazdowski, Marek Goc, Anna Godzik, Adam Goedecke, Wolfgang Goffeau, André Golebiewska Anna Goncharova, Rose Graham, Trevor Grąziewicz, Maria Grynkiewicz, Grzegorz Guzdek Amalia Grzybowska, Ewa Grzywna, Zbigniew Ludwik Hirszfeld Institute of Immunology, PAS, Wrocław Medical University of Lodz, Łódź Institute of Biochemistry and Biophysics, PAS, Warszawa Marceli Nencki Institute of Experimental Biology, PAS, Warszawa Universite Nice Sophia Antipolis, Nice University of Dundee, Dundee Imperial College, London Charles University, Prague Warsaw University of Life Sciences, Warszawa Pomeranian Medical University, Szczecin Palladin Institute of Biochemistry, NASU, Kyiv Laval University, Quebec Norwegian Institute for Air Research, Kjeller MSC Cancer Center and Institute of Oncology, Warszawa University of Wroclaw, Wrocław University of Riga, Riga Institute of Biophysics, Brno Institute of Bioorganic Chemistry, PAS, Poznań Institute of Jacques Monod, Paris MSC Cancer Center and Institute of Oncology, Gliwice Erasmus Medical Center, Rotterdam Universite Nice Sophia Antipolis, Nice Poznan University of Technology, Poznań German Cancer Research Center, Heidelberg Silesian University of Technology, Gliwice Medical University of Wroclaw, Wrocław UT Southwestern Medical Center, Dallas Computer-Chemie-Centre, Erlangen-Nurnberg CNRS, Nice Technische Universitat Dresden, Dresden Institute of Human Genetics, PAS, Poznań Institute of Bioorganic Chemistry, PAS, Poznań Leiden University Medical Center, Leiden Medical University of Lodz, Łódź Nicolaus Copernicus University, Toruń Joint Center for Structural Genomics, La Jolla University of Essen, Essen Institut des Sciences de la Vie, Louvain-la-Neuve Luxembourg Institute of Health, Luxembourg Institute of Genetics and Cytology, Minsk Queen Mary University of London, London Institute of Biochemistry and Biophysics, PAS, Warszawa Pharmaceutical Research Institute, Warszawa Jagiellonian University, Kraków MSC Cancer Center and Institute of Oncology, Gliwice Silesian University of Technology, Gliwice

Hamann, Ute Hancock, Ronald Handkiewicz-Junak, Daria Hannan, Ross Hansen, Lise L. Hanus, Jakub Hartman, Mariusz Hemminki, Kari Henkel, Corinna Hennig, Jacek Hennig, Wolfgang Hesse, Holger Hibner, Urszula Hoheisel, Jörg Hulmes, David Iżycki, Dariusz Jachymek, Wojciech Jakimowicz, Dagmara Jakóbisiak, Marek Jałoszyński, Paweł Janiak, Marek K. Janik, Przemysław Janiszewska, Joanna Jarząb, Barbara Jarząb, Michał Jażdżewski, Krystian Jelonek, Karol Jerzmanowski, Andrzej Jerzy Ostrowski Jurczak, Wojciech Jurka, Jerzy Kaminska, Bozena Kanthou, Chryso Kasten-Pisula, Ulla Kieda, Claudine Kimmel, Marek Kluiver, Joost Knappskog, Stian Komorowski, Jan Konieczny, Igor Konopa, Jerzy Konopka, Witold Kool, Marcel Kopitar, Natasha Koronacki, Jacek Korzeniewski Bernard German Cancer Research Center, Heidelberg Laval University Cancer Research Centre, Québec MSC Cancer Center and Institute of Oncology, Gliwice Research Division, Peter MacCallum Cancer Centre, Melbourne University of Aarhus, Aarhus Tulane University, New Orleans Medical University of Lodz, Łódź German Cancer Research Center, Heidelberg Ruhr University, Bochum Institute of Biochemistry and Biophysics, PAS, Warszawa Shanghai Institutes for Biological Sciences, Shanghai Max-Planck-Institute, Golm University of Montpellier, Montpellier German Cancer Research Center, Heidelberg Institut de Biologie et Chimie des Protéines, CNRS, Lyon Poznan University of Medical Sciences, Poznań Ludwik Hirszfeld Institute of Immunology, PAS, Wrocław Ludwik Hirszfeld Institute of Immunology, PAS, Wrocław Medical University of Warsaw, Warszawa Institute of Human Genetics, PAS, Poznań Military Institute of Hygiene and Epidemiology, Warszawa MSC Cancer Center and Institute of Oncology, Warszawa Institute of Human Genetics, PAS, Poznań MSC Cancer Center and Institute of Oncology, Gliwice MSC Cancer Center and Institute of Oncology, Gliwice Comprehensive Cancer Center, Columbus MSC Cancer Center and Institute of Oncology, Gliwice Institute of Biochemistry and Biophysics, PAS, Warszawa MSC Cancer Center and Institute of Oncology, Warszawa Jagiellonian University, Kraków Genetic Information Research Institute, Mountain View Marceli Nencki Institute of Experimental Biology, PAS, Warszawa Sheffield University, Sheffield Eppendorf University, Hamburg Centre for Molecular Biophysics, UPR 4301 CNRS, Orleans Rice University, Houston, Silesian University of Technology, Gliwice University of Groningen, Groningen University of Bergen, Bergen Uppsala University, Uppsala University of Gdansk, Gdańsk Gdansk University of Technology, Gdańsk German Cancer Research Center, Heidelberg German Cancer Research Center, Heidelberg Josef Stefan Institute, Ljubljana Institute of Computer Science, PAS, Warszawa Jagiellonian University, Kraków

Kowalczuk, Marek Kozomara, Ana Kreil, David P. Kreuzinger, Norbert Kruszewski, Marcin Krzysko Krystiana Krzyżosiak, Włodzimierz Kubiak, Jacek Kubicarowa, T. Kujawski, Maciej Kulma Anna Kumala, Sławomir Kupryjańczyk, Jolanta Kurzyńska-Kokorniak, Anna Lachowicz, Mirosław Larsson, Catharina Leluk, Jacek Leppek, Kathrin Lesyng, Bogdan Lévi, Francis Lichtarge, Olivier Limon, Janusz Lipniacki, Tomasz Lityńska, Anna Los, Marek Lotfi, Kourosh Lubiński, Jan Lukanova, Annekatrin Łuczkiewicz, Aneta Łukaszewicz, Marcin Macht, Marcus Madden, Timothy Magdziarz Tomasz Maier-Hein, Klaus H. Mairs, Rob Majchrzak, Henryk Majka, Jerzy Makałowska, Izabela Makałowski, Wojciech Malanga, Maria Małecki, Maciej Mansoor, Ahmed Marciniak-Czochra, Anna Marcon, Francesca Marczak, Łukasz Markiewicz, Ewa Centre of Polymer and Carbon Materials, PAS, Zabrze University of Manchester, Manchestr University of Natural Resources and Life Sciences, Vienna Vienna University of Technology, Vienna Institute Nuclear Chemistry and Technology, Warszawa University of Warsaw, Warszawa Institute of Bioorganic Chemistry, PAS, Poznań CNRS, Paris Institute of Biophysics, Brno Institute of Human Genetics, PAS, Poznań University of Wroclaw, Wrocław McGill University, Montreal MSC Cancer Center and Institute of Oncology, Warszawa Institute of Bioorganic Chemistry, PAS, Poznań University of Warsaw, Warszawa Pharmacology Biovitrum, Stockholm University of Zielona Góra, Zielona Góra German Cancer Research Center, Heidelberg University of Warsaw, Warszawa Warwick University Medical School, Coventry Baylor College of Medicine, Houston Medical University of Gdansk, Gdańsk Institute of Fundamental Technological Research, PAS, Warszawa Jagiellonian University, Kraków Linkoping University, Linkoping Linkoping University, Linkoping Pomeranian Medical University, Szczecin German Cancer Research Center, Heidelberg Gdansk University of Technology, Gdańsk University of Wroclaw, Wrocław Bruker Daltonics, Bremen University of Texas MD Anderson Cancer Center, Houston University of Silesia, Katowice German Cancer Research Center, Heidelberg UK Beatson Laboratories, Glasgow Silesian Medical University, Katowice Ludwik Hirszfeld Institute of Immunology, PAS, Wrocław Adam Mickiewicz University, Poznań Pennsylvania State University, University Park Institute for Veterinary Pharmacology and Toxicology, Zurich MSC Cancer Center and Institute of Oncology, Warszawa University of Miami, Miami University of Heidelberg, Heidelberg Istituto Supriore di Sanita, Rome Institute of Bioorganic Chemistry, PAS, Poznań University of Wroclaw, Wrocław

Markiewicz, Wojciech Martin Rachel Marszałek, Jarosław Masny, Aleksander Matter, Jean-Marc McKay, Bruce C. Meiss, Gregor Meister, Gunter Meriç Pagano, Süreyya Mielanczyk, Anna Mier, Walter Milcarz, Magdalena Mirowski, Marek Mosieniak, Grażyna Mothersill, Carmel Mouscadet, Jean Francois Motykiewicz, Grażyna Mozrzymas, Jerzy Mullenders, Leon H. Muller-Rober, Bernd Multhoff, Gabrielle Murphy, James Mycielska, Maria Nakielski, Jerzy Nauman, Paweł Niedźwiedź, Wojciech Nino, Ewa Nino, Jacques Noteborn, Mathieu H. Obolenskaya, Maria Oliński, Ryszard Ortmann, Elisabeth Ostrowski, Jerzy Ott, Sascha Palyvoda, Olena Pavanello, Sofia Pawlak, Andrzej Pawlas, Natalia Perkins, Neil D. Philmonienko, Vlada Pilc, Andrzej Pingoud, Alfred Pirsel, Miroslav Płucienniczak, Andrzej Polanski, Andrzej Polanski, Jaroslaw Institute of Bioorganic Chemistry, PAS, Poznań Shimadzu Biotech Kratos Analytical University of Gdańsk, Gdańsk Institute of Biotechnology and Antibiotics, Warszawa University of Lausanne, Lausanne Ottawa Hospital Research Institute, Ottawa Justus Liebig University, Giessen Regensburg University, Regensburg Namik Kemal University, Tekirdag Silesian University of Technology, Gliwice Universitätsklinikum Heidelberg, Heidelberg University of Wroclaw, Wrocław Medical University of Lodz, Łódź Marceli Nencki Institute of Experimental Biology, PAS, Warszawa McMaster University, Hamilton Ecole Normale Supérieure de Cachan CNRS, Cachan MSC Cancer Center and Institute of Oncology, Gliwice Wrocław Medical University, Wrocław Leiden University, Leiden University of Potsdam, Potsdam Technical University of Munich, Munich Institute of Technology Sligo, Ballinode Sligo Imperial College, London University of Silesia, Katowice Institute of Psychiatry and Neurology, Warszawa Oxford University, Oxford INSERM, Curie University, Paris Ecole Normale Superieure, Paris Biological Chemistry, Leiden University, Leiden Institute of Molecular Biology and Genetics, NAS, Kiev Nicolaus Copernicus University, Bydgoszcz University of Vienna, Vienna MSC Cancer Center and Institute of Oncology, Warszawa University of Warwick, Coventry Wayne State University, Detroit University of Padova, Padova Institute of Human Genetics, Poznań Institute of Occupational Medicine and Environmental Health, Sosnowiec Newcastle University, Newcastle Institute of Experimental Medicine, Prague Institute of Pharmacology, PAS, Kraków Justus Liebig University, Giessen Cancer Research Institute, SAS, Bratislava Institute of Biotechnology and Antibiotics, Warszawa Silesian University of Technology, Gliwice University of Silesia, Katowice

Polańska, Joanna Silesian University of Technology, Gliwice Poleszczuk, Jan University of Warsaw, Warszawa Priebe, Waldemar University of Texas, MD Anderson Cancer Center, Houston Prise, Kevin Gray Cancer Institute, Northwood Psiuk-Maksymowicz, Krzysztof Silesian University of Technology, Gliwice Rabakon Nadzeya Institute of Genetics and Cytology, Minsk Puszyński, Krzysztof Silesian University of Technology, Gliwice Radzikowski, Czesław Institute of Immunology and Experimental Therapy, Wrocław Rafat, Mehrdad Linköping University, Linköping Ratuszna, Alicja University of Silesia, Katowice Razin, Sergey Institute of Gene Biology, RAS, Moscow Reinke, Hans Medical University, Dusseldorf Rokita, Hanna Jagiellonian University, Kraków Rőmpp, Andreas Justus Liebig University, Giessen Rothkamm, Kai University of Saar, Homburg Rubi, Miguel Universitat de Barcelona, Barcelona Rybaczek Dorota Universityof Lodz, Lódź Rubi, Miquel Universitat de Barcelona, Barcelona Rusin, Aleksandra MSC Cancer Center and Institute of Oncology, Gliwice Rusin, Marek MSC Cancer Center and Institute of Oncology, Gliwice Rzepecki, Ryszard University of Wroclaw, Wrocław Rzeszowska-Wolny, Joanna Silesian University of Technology, Gliwice Sáfrány, Geza National Research Institute for Radiobiology and Radiohygiene, Budapest Sandness, Dagny University of Oslo, Oslo Sąsiadek, Maria Medical University of Wroclaw, Wrocław Schieck, Alexa Universitätsklinikum Heidelberg, Heidelberg Schluter, Urte Riso National Laboratory, Copenhagen Schueltke, Elisabeth Albert Ludwigs University, Freiburg Seymour, Colin McMaster University, Hamilton Sfakianakis, Nikolaos University of Mainz, Mainz Sherman Michael Y. Boston University School of Medicine, Boston Sherthan, Harry Institute of Radiobiology, Muenhen Shieck, Valentin Institute of Molecular Biology, RAS, Moscov Sidorenko, Svetlana Institute of Experimental Pathology and Oncology, Kiev Sidorik, Lyudmila Institute of Molecular Biology and Genetics, Kiev Siedlecki, Janusz MSC Cancer Center and Institute of Oncology, Warszawa Sieroń, Aleksander Medical University of Silesia, Katowice Sierra, Angels Bellvitge Biomedical Research Institute, IDIBELL, Barcelona Siewiński, Maciej Medical University of Wroclaw, Wrocław Sikora, Ewa Marceli Nencki Institute of Experimental Biology, Warszawa Silberring, Jerzy AGH University of Science and Technology, Kraków Simard, Martin Laval University, Quebec Simek, Krzysztof Silesian University of Technology, Gliwice Sirko, Agnieszka Institute of Biochemistry and Biophysics, PAS, Warszawa Sistonen, Lea Abo Academi University, Turku Sjakste, Nicolai University of Latvia, Riga

Składanowski, Andrzej M. Skonieczna, Magdalena Skrzydlewska, Ewa Skrzypczak, Magdalena Smolyakova, Raisa Smołka, Bogdan Staerk, Judith Staroń, Krzysztof Steffen, Jan Steinbrink, Sandra Strätling, Wolf H. Student, Sebastian Stühmer, Walter Svoboda, Petr Swinarew, Andrzej Sykorowa, Ewa Szabo, Gabor Szala, Stanisław Szaumkessel, Marcin Szeja, Wiesław Szewczyk, Adam Szołtysek, Katarzyna Szopa, Jan Sztajer, Helena Szumiel, Irena Szydło, Anna Szyfter, Krzysztof Ścieglińska, Dorota Świerniak, Andrzej Tarnawski, Rafał Tavassoli, Mahvash Teleman, Aurelio Tinhofer-Keilholz, Ingeborg Tomiałojć, Ludwik Trott, Klaus-Rudiger Tudek, Barbara Ugorski, Maciej Unold, Olgierd Urbanek, Ksymena Valiokas, Ramunas Van den Berg, Anke Van den Berghe, Wim Von Mikecz, Anna Walczak, Beata Walewski, Jan Wcisło, Gabriel Medical University of Gdańsk, Gdańsk Silesian University of Technology, Gliwice Medical University of Bialystok, Białystok MSC Cancer Center and Institute of Oncology, Warszawa Alexandrov Research Institute of Oncology and Medical Radiology, Minsk Silesian University of Technology, Gliwice University of Oslo, Oslo University of Warsaw, Warszawa MSC Cancer Center and Institute of Oncology, Warsaw German Cancer Research Center, Heidelberg Eppendorf University, Hamburg Silesian University of Technology, Gliwice Max-Planck Institute of Experimental Medicine, Göttingen Institute of Molecular Genetics, ASCR, Prague University of Silesia, Katowice Institute of Biophysics, Brno University of Debrecen, Debrecen MSC Cancer Center and Institute of Oncology, Gliwice Institute of Human Genetics, PAS, Poznan Silesian University of Technology, Gliwice Marceli Nencki Institute of Experimental Biology, PAS, Warszawa MSC Cancer Center and Institute of Oncology, Gliwice University of Wroclaw, Wrocław Technical University of Braunschweig, Braunschweig Institute Nuclear Chemistry and Technology, Warszawa Medical University of Silesia, Katowice Institute of Human Genetics, PAS, Poznań MSC Cancer Center and Institute of Oncology, Gliwice Silesian University of Technology, Gliwice MSC Cancer Center and Institute of Oncology, Gliwice King's College London, Guy's Hospital Campus, London German Cancer Research Center, Heidelberg Charite University, Berlin University of Wroclaw, Wroclaw Technical University of Munich, Munich Institute of Biochemistry and Biophysics, PAS, Warszawa Ludwik Hirszfeld Institute of Immunology, PAS, Wrocław Technical University of Wroclaw, Wrocław Medical University of Silesia, Katowice Center for Physical Sciences and Technology, Vilnius University of Groningen, Groningen University Antwerp, Antwerp Heinrich Heine University, Dusseldorf University of Silesia, Katowice MSC Cancer Center and Institute of Oncology, Warsaw Military Medical Institute, Warszawa

Wandzik, Ilona Silesian University of Technology, Gliwice Wegrowski, Yanusz CNRS MEDyC, Reims University, Reims Węgrzyn, Grzegorz Gdańsk University of Technology, Gdańsk Wesierski-Gadek, Józefa Medical University of Vienna, Vienna White, Steven University of California, Irvine Wideł, Maria Silesian University of Technology, Gliwice Widłak, Piotr MSC Cancer Center and Institute of Oncology, Gliwice Widłak, Wiesława MSC Cancer Center and Institute of Oncology, Gliwice Wiecheć, Emilia Linkoping University, Linkoping Wiemann, Stefan German Cancer Research Center, Heidelberg Wierzbicka, Małgorzata Institute of Human Genetics, PAS, Poznań Wilczyński, Grzegorz University of Wroclaw, Wrocław Wilson, Gareth Cancer Research UK, London Research Institute London, London Winkler, Frank German Cancer Research Center, Heidelberg Wiśniewski, Jacek R. Max-Planck-Institute for Biochemistry, Martinsried Wojdyła, Tomasz Silesian University of Technology, Gliwice Wójcik, Andrzej Stockholms Universitet, Stockholm Wróbel, Magdalena University of Wrocław, Wrocław Wyszko, Eliza Institute of Bioorganic Chemistry, PAS, Poznań Youdinkova, Elena Institute of Gene Biology, RAS, Moscow Xiao-Feng, Sun Linkoping University, Linkoping Xue, Ding University of Colorado, Boulder Zakrzewska, Jolanta Ludwik Hirszfeld Institute of Immunology, PAS, Wrocław Zanchetta, Luciene Institute of Technology SligoAsh Lane, Sligo Zdzienicka, Margaret University of Leiden, Leiden Ziembińska-Buczyńska, Aleksandra Silesian University of Technology, Gliwice Zimny, Janusz A. Plant Breeding and Aclimatization Institute, Radzików Żurawski, Marek NonoTemper Technologies, Munich Żylicz, Maciej International Institute of Molecular and Cellular Biology, Warszawa

Best Poster Presentations Awards of the Association for the Support of Cancer Research 2016 - Ewa Marek, Anna Lalik, Roman Jaksik: Stability of reference gene expression in cells exposed to stressing factors 2015 - Kristine Salmina, Anda Huna, Jekaterina Erenpreisa: Role of autophagy in survival of embryonal carcinoma cells treated with etoposide 2014 - Jolanta Guz, Daniel Gackowski, Marek Foksinski, Rafal Rozalski, Tomasz Dziaman, Ewelina Zarakowska, Anna Szpila, Ryszard Olinski: 5-methylcytosine, 5-hydroxymethylcytosine and 5- hydroxy-methyluracil in human leukocytes and sperm as epigenetic marks comparison of the absolute level 2013 - Jadwiga Pietkiewicz, Urszula Bazylińska, Joanna Rossowska, Anna Choromańska, Andrzej Gamian, Kazimiera Anna Wilk: Biocompatibility of nanoparticles loaded with photosensibilizers for practical use in support of anticancer therapy 2012 - Karol Ruszel, Paweł Kowalczyk, Agnieszka Maciejewska, Jarosław Kuśmierek: The effect of chloracetaldehyde on M13MP18 phage replicated in Escherichia coli JM 105 ALKB strain 2011 - Małgorzata Sekuła, Katarzyna Miękus, Marcin Majka: SDF-1/ITAC CXCR7 axis in biology of cervical carcinoma 2010 - Marek Żurawski: Generation of induced pluripotent stem cells from human mesenchymal and hematopoietic cells 2009 - Andriy Slonchak, Agata Chwieduk, Jhoanna Rzerzowska-Wolny, Maria Obolenska: Regulation of the human glutathione s-transferase P1 gene transcription 2008 - Wojciech Pigłowski, Piotr Filipczak, Zdzisław Krawczyk, Dorota Ścieglińska: Analysis of intracellular localization of the human HspA2 protein in cancer cells 2007 - Paweł Kowalczyk, Jolanta Jaworek, Michalina Kot, Beata Sokołowska, Aleksandra Bieleń, Beata Janowska, Jarosław M. Cieśla, Grzegorz Szparecki, Benita Sadom, Barbara Tudek: Inflammation increases oxidative DNA damage repair and stimulates preneoplastic changes in colons of newborn rats 2006 - Subbareddy Maddika, Emilia Wiechec, Lise-Lotte Hansen, Marek Los: Pro-apoptotic role of PI3- K/AKT pathway during apoptosis induced by selected anti-cancer drugs 2005 - Halina Waś, Tomasz Cichoń, Anna Ratajska, Anna Grochot, Barbara Węgiel, Agnieszka Łoboda, Agnieszka Jaźwa, Józef Dulak, Alicja Józkowicz: Effect of heme oxygenase-1 on proliferation, viability and angiogenic potential of melanoma cells in mice 2004 - Magdalena Kalinowska, Wojciech Garncarz, Monika Pietrowska, Piotr Widłak: Regulation of the human apoptotic nuclease endonuclease G 2003 - Ewa Ciesielska, Kazimierz Studzian, Elżbieta Żyner, Justyn Ochocki, Leszek Szmigiero: Cisplatin with aminoflavone wings as an improved apoptosis inducer of cancer cells 2002 - Wiesława Widłak, Witold Konopka, Anna Zborek, Dorota Ścieglińska, Zdzisław Krawczyk: GFP fluorescence in somatic cells of transgenic mice containing EGFP reporter gene under the control of the rat testis-specific hst70 gene promoter 2001 - Paweł Kowalczyk, Jarosław M. Cieśla, Maria-Anna Grąziewicz, Jarosław T. Kuśmierek, Barbara Tudek: DNA damage in P53 gene by chloroacetaldehyde and trans-4-hydroxy-2-nonenal 2000 - Olena Palyvoda, Piotr Widłak: Characterization of DFF40/CAD endonuclease - mediated pathway of apoptotic chromatin condensation