TERMS OF REFERENCE. Case reference: ADZ-23-19/2013

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1 TERMS OF REFERENCE Delivery of spinning-disk confocal microscope for live cell imaging in real-time for the International Institute of Molecular and Cell Biology in Warsaw Case reference: ADZ-23-19/2013 Public procurement procedure for a contract with the value in excess of EU thresholds to be awarded as a public procurement contract under an open tender procedure, pursuant to the Public Procurement Act of 29 January 2004 (Journal of Laws 2010, No. 113, item 759 with later amendments) Warsaw,

2 I. THE CONTRACTING AUTHORITY International Institute of Molecular and Cell Biology, 4 Ks. Trojdena Street, Warsaw, Poland Phone:(+48 22) , Fax: ( ) , II. TYPE OF AWARD The procedure is conducted under the Public Procurement Act of 29 January 2004 (Journal of Laws 2010, No. 113, item 759 with later amendments), hereinafter referred to as the "PPA", under an open tender procedure for the supply of contract value exceeding the amount specified in the provisions issued pursuant to the Article 11, section 8 of the PPA III. DESCRIPTION OF THE SUBJECT MATTER OF THE CONTRACT 1. The subject matter of the contract is the delivery of a spinning-disk confocal microscope for live cell imaging in real-time for the International Institute of Molecular and Cell Biology in Warsaw 2. CPV: Fluorescent microscopes 3. The subject matter of the contract shall cover the delivery and installation of imaging system consisting of inverted fluorescence microscope, spinning-disk confocal scanner, laser module and workstation with software for system control and data acquisition. The subject matter of the contract shall also include user training with regard to operation of the whole equipment. A detailed description of the subject of the contract, along with an itemized list of the required technical parameters, is provided in Enclosure No. 2 to the Terms of Reference - Technical Parameters of the Subject Matter of the Contract. 4. Requirements concerning the subject matter of the contract: a) The contract includes delivery of new equipment, free from any faults, based on latest technological concepts of the manufacturer, together with new, original components, in accordance with the norms being in force in Poland. b) Warranty: at least 36 months on cameras, at least 24 months on spinning-disk confocal scanner, at least 12 months on other components of the system. c) Warranty service authorized by the equipment manufacturer, provided on the terms described in Enclosure No. 7 to the Terms of Reference - Draft Agreement, d) Operation manuals in the English language - enclosed with the delivered equipment, e) Original manufacturer's catalogues (technical documentation) providing a detailed description of the technical parameters of the equipment offered under the contract (the Contracting Authority shall accept print-outs from the manufacturer's website), 5. The Contracting Authority does not provide choice of the best bid with the use of an electronic auction, referred to in the article 91a - 91c of the PPA. 6. The contracting authority does not provide for framework agreement. 7. No partial bids are allowed as specified in Article 2 section 6 of the PPA 8. No variant bids are allowed as specified in Article 2 section 7 of the PPA 9. The Contracting Authority does not expect that supplementary contracts be awarded, as specified in Article 67 section 1 item 7 of the PPA. 2

3 10. The contracting authority does not provide for settlements in foreign currency 11. The contracting authority does not provide for advance payments, as specified in Article 151a of the PPA. IV. CONTRACT DELIVERY DEADLINE The required date of contract execution is by December 30, 2013 V. CONDITIONS FOR PARTICIPATION IN THE PROCEDURE AND DESCRIPTION OF THE METHOD USED FOR THE EVALUATION OF THE FULFILMENT THEREOF 1. Contractors eligible to participate in the tender procedure are those which meet the criteria specified in Article 22 section 1, i.e.: a) hold necessary qualifications/authorisations to perform specific activities or operations if such qualifications/authorisations are required by law; b) have the necessary knowledge and experience; c) have at their disposal the necessary technical potential and personnel capable of performance under the contract; d) are in an appropriate economic and financial position guaranteeing the performance of the contract. 2. The description of how to fulfil the conditions: a) The condition of having the necessary knowledge and experience - the Contracting Authority will consider the condition fulfilled when the Contractor: - proves that in the last three years prior to the submission deadline, and if the activity period is shorter - in this period, duly executed, and in the case of periodic or continuous operation also performs, at least two successful deliveries of microscopy systems - worth gross not less than PLN each. Note: In the case of contracts concluded in foreign currency, the value of the deliveries should be converted using the average exchange rate of foreign currency published by the National Bank of Poland for the date of an agreement confirming the delivery of research equipment. b) The condition of being in an appropriate economic and financial position the Contracting Authority will consider the condition fulfilled when the Contractor: - proves that it has as of a date of submission of tender bids a valid civil liability insurance in respect to its activities related to the subject matter of the contract, in an amount of at least PLN Note: In the case of contracts concluded in foreign currency, the value of the policy should be converted using the average exchange rate of foreign currency published by the National Bank Poland on the date of the insurance contract. 3. Contractors who apply jointly for the award of the contract meet the terms and conditions mentioned in Chapter V.2 letters a, b of the Terms of Reference cumulatively 4. The criteria listed above shall be assessed on the basis of the documents and statements, mentioned in Chapter VI section 1 and 2 of the Terms of Reference, submitted by the Contractor, using the "does meet the criteria - does not meet the criteria" formula 5. Subject to article 26 section 3 of the PPA, if the Contractor fails to attach to the bid the required statements and documents or their contents do not show that the conditions for the participation in the procedure are met, the Contracting Authority will exclude the Contractor pursuant to the article 24 section 2.4 of the PPA. 3

4 VI. LIST OF STATEMENTS AND DOCUMENTS TO BE SUBMITTED BY CONTRACTORS 1. In order to confirm that they fulfil the conditions for participating in the contract award procedure as per Art. 22 section 1 of the PPA, the Contractors have to enclose with their tender bid the following documents and statements: 1.1. Eligibility statement concerning compliance with eligibility criteria specified in Article 22 section 1 of the PPA (sample copy attached as Enclosure no. 3 to the Terms of Reference); 1.2. List of deliveries or services provided and, in the case of periodic or continuous supplies or services, also a list of ongoing supplies or services within the scope necessary to prove that the knowledge and experience criteria are met, provided within the period of past three years prior to the bid submission deadline or, if the duration of economic operations is shorter, during that period - including information on the type, value, date and place of execution and the name of the client, and enclosing documents attesting that these deliveries were provided or are being provided properly (sample copy attached as Enclosure 6 to the Terms of Reference); 1.3. Paid insurance or other evidence that the Contractor is insured against civil liability in respect of its activities related to the contract. 2. In order to prove lack of grounds for exclusion as regards Art. 24 section 1 of the PPA, the Contractor has an obligation to enclose with its tender bid the following documents and statements: 2.1. Statement that there are no grounds for exclusion from participation in the procedure (sample copy attached as Enclosure 4 to the Terms of Reference); 2.2. Current extract from a relevant register, if separate regulations require an entry in the register, issued not earlier than 6 months before the bid submission deadline, and as regards natural persons, a statement in relation to Art. 24 section 1.2 of the PPA; 2.3. Current certificate issued by Head of the competent Tax Office confirming that the Contractor does not have any overdue liabilities representing taxes or a certificate that the Contractor has obtained a legally allowed exemption, extension or arrangement to pay in instalments the Contractor's overdue liabilities or that the enforcement of the decision of the relevant authority has been suspended in its entirety - issued no earlier than 3 months before the submission deadline; 2.4. Current certificate issued by a competent branch of the Social Security Institution (ZUS) or Agricultural Social Insurance Fund (KRUS) to confirm that the Contractor does not have any overdue social security or health insurance contributions, or a certificate that the Contractor has obtained a legally allowed exemption, extension or arrangement to pay in instalments the Contractor's overdue liabilities or that the enforcement of the decision of the relevant authority has been suspended in its entirety - issued no earlier than 3 months before bid submission deadline; 2.5. Statement on affiliation with or lack of affiliation to a corporate group, within the meaning of the Act on Competition and Consumer Protection of February 16, 2007 (Journal of Laws No 50, item 331, with later amendments) together with the list of subjects belonging to the same corporate group (Enclosure 5 to the Terms of Reference); 2.6. Current information from the National Register of Criminal Records within the scope specified in Article 24 section 1 items 4)-8) of the Act, issued not earlier than 6 4

5 months before the bid submission deadline; 2.7. Current information from the National Register of Criminal Records within the scope specified in Article 24 section 1 item 9) of the Act, issued not earlier than 6 months before the bid submission deadline; 2.8. If, in the case of a Contractor whose registered office is located in the territory of the Republic of Poland, persons referred to in Article 24 section 1 items 5-8, 10 and 11 of the PPA are residents outside the territory of the Republic of Poland, the Contractor shall submit, in relation to such persons, a criminal records check document issued by a judiciary or administrative authority with jurisdiction by reason of their domicile to the extent as specified in Article 24 section 1 items 5-8, 10 and 11 of the PPA, issued not earlier than 6 months prior to the bid submission deadline, and if in the place of residence such documents are not issued - they should be substituted with a document containing a statement made before a notary public, a competent judicial or administrative authority or a professional or business association authority with jurisdiction by reason of domicile of such persons 3. If the Contractor's registered office or place of residence is located outside the territory of the Republic of Poland, the Contractor shall substitute the documents described in Chapter VI section 2, items and 2.7 of the Terms of Reference, with the following documents: 1) a document or documents issued in the country where the Contractor has its registered office or place of residence, respectively confirming that a) no liquidation proceedings against the Contractor have been initiated and the Contractor has not been declared bankrupt; b) the Contractor is not overdue with the payment of any taxes, charges or social security or health insurance contributions, or that the Contractor has obtained a legally allowed exemption, extension or arrangement to pay in instalments the Contractor's overdue liabilities or that the enforcement of the decision of the relevant authority has been suspended in its entirety; c) no ruling which bans the Contractor from bidding for the contract has been issued; 2) a certificate issued by a competent judiciary or administrative authority in the Contractor's country of residence or the country of residence of the person the documents refer to, to the extent specified in Article 24 section 1 items 4-8, 10 and 11 of the PPA - issued not earlier than 6 months before the bid submission deadline. 4. The documents referred to in Chapter VI, section 3 items 1a, 1c and item 2 of the Terms of Reference should be issued not earlier than 6 months before the bid submission deadline, and the document referred to in Chapter VI, section 3 item 1b of the Terms of Reference not earlier than 3 months before the bid submission deadline. 5. If the documents mentioned in Chapter 6, section 3 items 1-2 of the Terms of Reference are not issued in the country where the Contractor has its registered office or place of residence, they should be substituted with a written statement, indicating also legal representatives of the Contractor, prepared before a notary public, a competent judicial or administrative authority or a professional or business association authority, respectively in the country of origin of the person or the country where the Contractor has the registered office or place of residence. 5

6 3. To confirm that the subject matter of the contract meets the requirements determined by the Contracting Authority, the Contractor should enclose with its tender bid the following documents: 1) Description of the technical parameters of the offered equipment (sample copy attached as Enclosure No 2 to the Terms of Reference); 2) Technical documentation from the manufacturer of the offered equipment (original catalogue) and manufacturer's documentation confirming that the technical parameters declared in Enclosure No. 2 to the Terms of References are met. Print-outs from websites are allowed. 3) Service authorization document issued by the equipment manufacturer or written declaration of the manufacturer that equipment will be serviced by the manufacturer VII. FORMAL REQUIREMENTS FOR SUBMITTED DOCUMENTS 1. All documents shall be submitted as originals or copies certified to be true copies by persons authorised to represent the Contractor. 2. Should a copy submitted by the Contractor be illegible or should it raise any doubts as to its authenticity, the Contracting Authority may request that either the original or a copy certified by a notary public to be a true copy be presented. 3. All documents drawn up in a foreign language must be submitted along with their Polish translation (except for documents drawn up in English). The Contracting Authority will accept bids in English 4. If the Contractor is represented by a proxy, a relevant Power of Attorney must be attached to the tender bid, defining the scope of powers, and the Power of Attorney must be signed by persons authorized to represent the Contractor. If a copy of the Power of Attorney is attached, its conformity with the original must be confirmed by the person who granted the power of attorney with the phrase "certified to be a true copy." 5. In the event a bid is submitted by a civil law partnership, documents referred to in Chapter VI, section 1 item 1.1 as well as section 2 items should apply to each of the partners of the partnership 6. The Contractors forming a consortium applying for the award jointly shall appoint an attorney to represent them in the proceedings or represent them in the proceedings and conclude a public procurement contract. The power of attorney must be attached to the bid. If the Contracting Authority selects the bid made by the consortium, the Contractors forming the consortium will be required, before signing the procurement contract at the latest, to submit a consortium agreement. The documents referred to in Chapter VI, section 2 shall be submitted by the consortium members separately. The declaration referred to in Chapter VI. section 1 item 1.1, and evidence of knowledge and experience, and the availability of appropriate technical potential and personnel capable of performing the contract and supporting the economic and financial situation to enable execution of the contract shall be assessed jointly. VIII. INFORMATION ON COMMUNICATION BETWEEN THE CONTRACTING AUTHORITY AND THE CONTRACTORS AND TRANSFER OF DECLARATIONS AND DOCUMENTS, AS WELL AS A LIST OF PERSONS AUTHORIZED TO COMMUNICATE WITH THE CONTRACTORS 1. Pursuant to Article 27 of the PPA, any statements, applications, notifications and 6

7 information between the Contracting Authority and the Contractors shall be exchanged in writing to the address of the Contracting Authority: Międzynarodowy Instytut Biologii Molekularnej i Komórkowej, ul. Ks. Trojdena 4, Warszawa, 2. Except for the restriction stipulated in Chapter VIII section 3 of the Terms of Reference, the Contracting Authority allows for communication with the Contractors by fax number , or to the address: przetargi@iimcb.gov.pl 3. A written form is restricted for submission of a bid and enclosures, including declarations and documents confirming the Contractor meets the requirements to participate in the proceedings, and declarations and documents confirming that a bid is compliant with the requirements established by the Contracting Authority, as well as amendment or cancellation of a bid. 4. Any statements, motions, notifications and information sent by fax or shall be confirmed, on request of the other party, immediately upon receipt thereof and the time and date of its delivery shall be indicated. 5. The Contracting Authority does not foresee any advice, answers or explanations be given orally or by phone in reply to questions which require written procedure. 6. The Contracting Authority accepts any letters concerning the procedure during its working hours, i.e. from Monday to Friday, 9.00 am to 5.00 pm. 7. Persons authorized to communicate with the Contractors: Mr. Tomasz Węgierski, Ms. Anna Brzezińska IX. TENDER BOND REQUIREMENTS 1. The Contracting Authority requires a tender bond of PLN 15, The tender bond shall be paid before the bid submission deadline, and if the bond is paid in the form of a deposit by bank transfer, the date regarded as the date of payment shall be the date when the deposit amount is credited to the bank account of the Contracting Authority. 3. The tender bond may be in the form of : a) money deposit by bank transfer, with payment title given as "wadium, nr sprawy ADZ-23-19/2013 [tender bond, case ref...] to the Contracting Authority's bank account no: BPH b) sureties issued by a bank or a savings-and-credit union, with the provision that a savings-and-credit union surety must always be a cash bond, c) bank guarantees, d) insurance guarantees e) sureties issued by entities specified in Article 6b section 5 item 2 of the Act on the establishment of the Polish Agency for Entrepreneurship Development (Polska Agencja Rozwoju Przedsiębiorczości) of November 9, A paid tender bond shall be kept by the Contracting Authority on a bank account. 5. Any bids not secured by a tender bond shall be rejected. 6. A copy of the document confirming that the tender bond has been paid/delivered must be attached to the tender bid. X. TIME LIMIT FOR BEING BOUND BY THE TENDER BID: 1. The Contractor shall be bound by the tender bid for a period of 60 days, starting from the day when the bid submission deadline expires 2. The Contractor may on its own, or at request of the Contracting Authority, extend the time limit for being bound by the tender bid, however the Contracting Authority may only 7

8 once ask the Contractor to agree to extend that time limit by a set period of time not longer than 60 days, at least 3 days before the expiry of the time limit for being bound by the tender bid. XI. HOW TO PREPARE A TENDER BID: 1. The contents of the submitted tender bid must conform to these Terms of Reference. The Contractor has the right to submit only one tender bid for the subject matter of the contract. 2. To be valid, the tender bid must be submitted in writing, in the Polish language. However; the Contracting Authority allows the tender bid and/or other documents to be submitted in the English language. 3. No electronic tender bids are allowed 4. The tender bid form and all required forms, statements and other enclosed documents must be signed by the persons authorized to represent the Contractor in business transactions, in accordance with registration documents and statutory requirements. 5. If the bid and the appendices thereto are signed by a representative of the Contractor acting under a power of attorney, the relevant power of attorney document should be enclosed. The power of attorney must contain a clause authorizing its holder to represent the Contractor in the tender procedure, or to both represent the Contractor in the tender procedure and enter into the contract. 6. Any amendments or changes to the contents of the tender bid must be signed by persons authorized to represent the Contractor. 7. The Contractor may stipulate that any part of the tender bid which contains business secrets in the meaning of the regulations on counteracting unfair competition shall be kept confidential. 8. It is recommended that the confidential part of the tender bid be placed in a separate envelope marked as "Informacje zastrzeżone jako tajemnica przedsiębiorstwa" ("Confidential information representing business secrets"). 9. All the documents representing the tender bid shall be firmly bound/stapled together. 10. The bid shall be submitted in a non-transparent, closed envelope, which should be addressed to the Contracting Authority and marked as follows: Międzynarodowy Instytut Biologii Molekularnej i Komórkowej, ul. Ks. Trojdena 4, Warszawa oferta na: Dostawę mikroskopu konfokalnego z wirującym dyskiem do przyżyciowego obrazowania komórek w czasie rzeczywistym na potrzeby Międzynarodowego Instytutu Biologii Molekularnej i Komórkowej w Warszawie Znak sprawy: ADZ-23-19/2013, Nie otwierać przed dniem 31 października 2013 r. godz The envelope should bear the name and address of the Contractor. 12. The Contractor may amend or withdraw its tender bid, provided it does so before the bid submission deadline. Both an amendment to, and withdrawal of, the tender bid must be supported by a statement in writing. Any changes in the contents of the bid accompanied by a supporting statement of changes having been made should be prepared, enveloped and addressed in the same manner as the tender bid and designated with the word "ZMIANA [amendment]". 8

9 13. A written statement of withdrawal of the tender bid should be enveloped and addressed in the same manner as the tender bid and designated with the word "WYCOFANIE [withdrawal]". XII. PLACE AND DATE OF TENDER BID SUBMISSION AND OPENING OF TENDER BIDS 1. Tender bids shall be submitted at the registered office of the Contracting Authority (Building D, room 004). 2. The bid submission deadline shall expire on October 31, 2013 at 12:00 pm. 3. Bids received by the Contracting Authority after the deadline shall be returned to the bidders unopened, after the expiry of the time limit for lodging a protest. 4. The tender bids shall be opened during a meeting on October 31, 2013 at 12:30 pm, at the registered office of the Contracting Authority, room The bid opening session shall be open to the public. 6. Directly before the opening of the bids, the Contracting Authority shall announce the amount of money at its disposal to finance the contract. 7. During the bid opening session, the names and addresses of Contractors shall be read out, along with the information concerning the price, time limit for the completion of the contract, warranty period and terms of payment included in the tender bids. All these data shall be immediately recorded in the minutes of the tender procedure. 8. The information, referred to under item 7, shall be sent to Contractors that were absent from the bid opening session, upon their request in writing. XIII. DESCRIPTION OF TENDER PRICE CALCULATION METHOD 1. The Contractor has an obligation to calculate the price for all the requirements of the Contracting Authority specified in the Terms of Reference. 2. The price quoted in the tender bid must fully cover all the costs related to execution of the contract. 3. The tender bid must provide the net price and the gross price for the contract, as well as the amount of VAT. The Contractors that are not VAT payers shall only provide the net price. 4. The prices quoted in the form should be expressed in PLN ( Polish złoty ) and calculated with an accuracy of two decimal places ( grosz ), in accordance with paragraph 5 section 7 of the Minister of Finance Regulation of December 11, 2012, that has changed the regulation on tax return to some tax payers (Journal of Laws No 0, item 1428). The bid price shall be rounded to full grosz, with the provision that endings below 0,5 grosz shall be omitted and endings equal or higher than 0,5 grosz shall be rounded up to one grosz. 5. Any settlements between the Contracting Authority and the Contractor shall be made in PLN. 6. For Contractors with the registered office, permanent operations facility or permanent residence outside the territory of the Republic of Poland, the Contracting Authority shall increase the tender net price by adding to it the amount of VAT applicable under Polish tax regulations and, if applicable, customs duties, for the sole purpose of bid comparison and assessment. The agreement shall be signed using the net price, and VAT will be paid by the Contracting Authority. 7. The ordered equipment shall be imposed with 23% VAT rate. If the Contractor uses a different VAT rate, the Contractor must enclose a document proving that the equipment is 9

10 eligible for a different tax rate (the basis for different tax rate, regulations, individual interpretations), as well as a detailed list of net prices, gross prices, VAT rates for individual pieces of equipment. XIV. BID ASSESSMENT CRITERIA 1. The Contracting Authority shall select the best tender bid, not subject to rejection, of the lowest gross price, which shall consequently obtain the biggest number of points. 2. The Contracting Authority shall make an assessment of the tender bids on the basis of the following criterion: No Criterion Weight Maximum number of points a bid may obtain under a given criterion 1. Gross price 100% 100 P Points for the price of the tender bid shall be calculated according to the following formula: lowest gross price of the bid C = x 100 Gross price of the bid assessed XV. INFORMATION ON FORMALITIES TO BE COMPLETED AFTER THE SELECTION OF THE WINNING BID IN ORDER TO EXECUTE A CONTRACT UNDER PUBLIC PROCUREMENT PROCEDURE 1. Immediately upon selection of the best tender bid, the Contracting Authority shall notify the Contractors who submitted their bids of: a) the selection of the best bid, providing the name (business name) or first name and surname, registered office or place of residence of the selected Contractor, along with the justification of the selection made, as well as the company names or first name and surname, registered offices or place of residence of the Contractors who submitted their bids, along with the number of points awarded to each bid on each criterion and the total number of points awarded; b) the Contractors whose tender bids have been rejected, providing factual and legal justification thereof; c) the Contractors who have been excluded from the tender procedure, providing factual and legal justification thereof; d) the deadline after which the public procurement agreement may be concluded. 2. An agreement with the selected Contractor shall be signed within not less than 10 days from the date of the notification of the bid selection, and no later than before the expiry of the period of being bound by the bid. 3. Should the Contractor whose bid was selected evade to enter into a contract under public procurement proceedings or fail to provide the performance bond, if required, the Contracting Authority may select the best bid from the remaining bids, unless there are circumstances mentioned in Article 93 section 1 of the Act. XVI.MATERIAL PROVISIONS OF THE CONTRACT 10

11 1. Material provisions of the contract are provided in the draft agreement which is represented by Enclosure 7 to the Terms of Reference. 2. Pursuant to Article 144 section 1 of the PPA the Contracting Authority allows the possibility to make changes to the contents of the agreement with regard to the contents of the tender bid, which provided the basis for the selection of the Contractor, in the case of: a) changes in the regulations of public law to the extent that would affect the execution of the contract the contents of the agreement will be adjusted to the new regulations b) an act of God being a force majeure event preventing timely performance under the contract - the contract completion deadline may be amended, accordingly (following agreement between the parties); c) withdrawal from sales or unavailability of the offered model the equipment may be replaced by equivalent equipment with parameters not worse than those provided by the Terms of Reference 3. The Contracting Authority does not require that the Contractor provides a performance bond 4. The Contracting Authority reserves the right to withdraw from the agreement in case the Contractor fails to deliver the equipment and the invoice to the Contracting Authority s office by December 30, XVII. INFORMATION ON LEGAL PROTECTION MEASURES AVAILABLE TO THE CONTRACTOR IN THE COURSE OF THE TENDER AWARD PROCEDURE The Contractors whose legal interest in being awarded the contract has been compromised as a result of the breach by the Contracting Authority of the provisions of the Public Procurement Act of 29 January 2004 (as amended on 7 April 2006) shall have the right to appeal, as provided for in the aforementioned Act. XVIII. OTHER PROVISIONS In matters not regulated in these Terms of Reference, the applicable regulations shall be those of the Public Procurement Act and the Civil Code XIX. LIST OF ENCLOSURES Enclosure No. 1 - Tender Bid Form Enclosure No. 2 - Technical parameters Enclosure No. 3 - Contractor's Statement on fulfilment of eligibility conditions, in accordance with Article 22, section 1 of the PPA Enclosure No. 4 - Contractor's Declaration of lack of grounds for exclusion from the contract award procedure Enclosure No. 5 - Contractor's Statement on Affiliation with a corporate group, as specified in Article 24, section 1, item 5 of the PPA Enclosure No. 6 - List of Contracts/Deliveries Enclosure No. 7 - Draft Agreement APPROVED BY:. Date and signature of the Head of the Unit 11

12 Enclosure 1 to the Terms of Reference (Contractor s stamp) ( place and date) TENDER BID FORM Contractor's Name:... Address:..) NIP (Tax ID Number):.. Telephone:. Fax: Contact person:.. In response to the announcement concerning a public procurement contract under an open tender procedure for the delivery of a spinning-disk confocal microscope for live cell imaging in real-time for the International Institute of Molecular and Cell Biology in Warsaw, case reference No ADZ-23-19/2013, we submit hereby our tender bid: 1. Net bid price (without VAT):. PLN (say: ) VAT (...%) :... Gross bid price (with VAT)*) :..... PLN (say: ) spinning-disk confocal microscope for live cell imaging in real-time, as specified by the requirements given in Table 1 Enclosure No 2 /indicate name, model and manufacturer/ *) The Contractors that are not VAT payers should only provide the net price 2. Delivery deadline for the public procurement contract: until December 30, Warranty on cameras: 36 months. 4. Warranty on spinning-disk scanner: 24 months 5. Warranty on other components: 12 months We also declare that: 1. We know the requirements specified in the Terms of Reference and that we have received all information necessary to prepare our tender bid and accept these conditions without any objections. 2. We accept the period through which we shall be bound by this tender bid to be 60 days, as indicated in the Terms of Reference. 3. Should our tender bid be accepted, we undertake to enter into a contract on the terms stipulated in the Terms of Reference, at the place and date indicated by the Contracting Authority. 12

13 Enclosure 1 to the Terms of Reference 4. We intend to subcontract part of the contract, i.e.:...../ the contract shall not be subcontracted ** 5. Subcontractors involved in performing the contract,.... (business names), have the knowledge and experience necessary to perform the contract, this declaration is accompanied by a written guarantee of the said undertakings that they will participate in performing the contract.** 6. List of documents which make an integral part of this tender bid: 1) Tender Bid Form (Enclosure No. 1 to the Terms of Reference) 2) Power of attorney to represent the Contractor in the tender procedure** (if applicable), 3) Contractor's Statement on fulfilment of eligibility conditions (Enclosure No. 3 to the Terms of Reference) 4) Contractor's Statement on affiliation with a corporate group, as specified in Article 24, section 1, item 5 of the PPA (Enclosure No. 5 to the Terms of Reference) 5) Current Liability Insurance Policy or other insurance document 6) List of past contracts/deliveries, with enclosures confirming due performance thereunder (Enclosure no. 6 to the Terms of Reference), 7) Contractor's Declaration of lack of grounds for exclusion from the contract award procedure (Enclosure No. 4 to the Terms of Reference), 8) Excerpt of entry in the National Court Register (KRS)/ Certificate of entry in the business entities register **), 9) Current certificate from the Head of a competent Tax Office, 10) Current certificate from a relevant Branch of Social Security Institution/Agricultural Social Insurance Fund (ZUS/KRUS)** 11) Current information from the National Register of Criminal Records, 12) Technical Specification of the Subject matter of the Contract (Enclosure No. 2 to the Terms of Reference) 13) Catalogue, technical documentation or printouts from manufacturer or distributor for the offered equipment proving that required technical parameters, as specified in the Enclosure No 2, are fulfilled. 14) Service authorization document issued by the equipment manufacturer or written declaration of the manufacturer that equipment will be serviced by the manufacturer 15) Copy of tender bond confirmation document We submit our complete tender bid on.. consecutively numbered pages.. First and Last name and signature of the Contractor or its authorized representative **) cross out whichever does not apply 13

14 Enclosure No 2 to the Terms of Reference Case reference ADZ-23-19/2013 item TECHNICAL SPECIFICATION OF THE SUBJECT OF THE CONTRACT Table 1. spinning-disk confocal microscope for live cell imaging in real-time 1 piece. Lp Opis urządzenia wraz z wymaganymi podzespołami, funkcjami i parametrami Description of equipment with required subcomponents, functions and parameters Nazwa producenta i model lub oferowany podzespół/funkcja/parametr (tak/nie/ wartość) Producer and model or offered subcomponent/function/ parameter (yes/no/value) Zmotoryzowany mikroskop fluorescencyjny na statywie odwróconym z palnikiem ksenonowym i kontrastem Nomarskiego Motorized inverted fluorescence microscope with xenon burner and Nomarski contrast 1 Zmotoryzowany mikroskop fluorescencyjny na statywie odwróconym z następującymi podzespołami, funkcjami i parametrami: Motorized inverted fluorescence microscope with following subcomponents, functions and parameters: 2 Oświetlacz LED światła białego lub halogenowy 100 W do obrazowania w świetle przechodzącym White-light LED or 100W halogen illuminator for transmitted light imaging 3 Kondensor wraz z polaryzatorem i pryzmatem do kontrastu Nomarskiego przy wykorzystaniu obiektywów wymienionych w pkt. 8 i 9 Condensor with polarizer and DIC prism for lenses given in #8 and #9 4 Analizator do kontrastu Nomarskiego DIC analyzer 5 Zmotoryzowany port boczny pracujący w układzie 100% okular, 100% port lewy, 100% port prawy Motorized port switch between 100% eyepieces, 100% left port, 100% right port 6 Osłona od kurzu Dust cover 7 6-pozycyjny zmotoryzowany rewolwer na obiektywy 6-position motorized objective revolver 8 Obiektyw klasy apochromat z korekcją pola, o powiększeniu 60-63x i stałej numerycznej aperturze 1.4, imersja olejowa, do szkiełek 0.17 mm, wraz z pryzmatem do kontrastu Nomarskiego Apochromat oil objective 60-63x, with constant NA 1.4, flat-field corrected, for 0.17mm coverslips, delivered together with DIC prism /podać nazwę producenta i /indicate producer and 14

15 Enclosure No 2 to the Terms of Reference 9 Obiektyw o imersji olejowej o powiększeniu 40x i stałej numerycznej aperturze 1.3, o poziomie transmisji 30% przy 340 nm, do szkiełek 0.17 mm, wraz z pryzmatem do kontrastu Nomarskiego Oil objective 40x, with constant NA 1.3, transmission 30% at 340 nm, for 0.17mm coverslips, delivered together with DIC prism 10 Obiektyw nieimersyjny, z korekcją pola, o powiększeniu 20x i numerycznej aperturze 0.5, do szkiełek 0.17 mm Dry objective 20x, NA 0.5, flat-field corrected for 0.17mm coverslips 11 Oświetlacz do fluorescencji z palnikiem ksenonowym W, mocowany na statywie mikroskopu bądź podłączony za pomocą światłowodu dostosowanego do transmisji światła o długości fali w zakresie nm, wraz z zasilaczem Illuminator with W xenon burner, attached directly to microscope stand or via optic fiber transmissible for nm light, together with power supply 12 Zmotoryzowane koło filtrów wzbudzania o średnicy filtrów 25mm, 8-10 pozycji, o czasie zmiany sąsiadujących filtrów 35 ms lub krótszym, wraz z szybką migawką Motorized excitation filter wheel, for 8-10 filters with 25mm diameter; switch time between adjacent positions 35 ms or faster 13 6-pozycyjny zmotoryzowany reflektor filtrów fluorescencyjnych wraz z 3-6 kostkami na filtry 6-position motorized reflector turret with 3-6 filter cubes 14 Zestaw filtrów do obrazowania Fura-2, składający się z dwóch filtrów wzbudzania z maks. transmisji przy długościach fali 340 ±5 nm i 385 ±5 nm (pasujące do koła filtrów z pkt. 12), lustra dichroicznego i filtru emisyjnego z cetrum transmisji wokół 510 ±5 nm (pasujące do kostek z pkt. 13) Fura-2 filter set, consisting of two excitation filters with max transmission at 340 ±5 nm and 385 ±5 nm (for filter wheel given in #12), dichroic and emission filter with peak centered at 510 ±5 nm (for cubes given in #13) 15 Zestaw filtrów do obrazowania DAPI/GFP/TRITC/Cy5 składający się z osobnych czterech filtrów wzbudzania dla każdego wymienionego barwnika (pasujące do koła filtrów z pkt. 12), poczwórnego lustra dichroicznego i poczwórnego filtru emisyjnego (pasujące do 15

16 Enclosure No 2 to the Terms of Reference kostek z pkt. 13) DAPI/GFP/TRITC/Cy5 quad filter set consisting of four independent excitation filters for listed fluorophores (for filter wheel given in #12), quad dichroic and quad emission filter (for cubes given in #13) 16 Zestaw filtrów do obrazowania GFP/YFP, składający się z filtru wzbudzania z centrum transmisji wokół 500 ±5 nm, lustra dichroicznego 515 ±2 nm, i filtru emisyjnego z cetrum transmisji wokół 535 ±5 nm (zestaw pasujący do kostek z pkt. 13) GFP/YFP filter set consisting of single excitation filter with peak centered at 500 ±5 nm, 515 ±2 nm dichroic, and single emission filter with peak centered at 535 ±5 nm (for cubes given in #13) 17 Zmotoryzowany układ zmiany powiększenia wewnątrz mikroskopu z soczewkami 1x oraz 1.6x Motorized internal magnification changer with lenses 1x and 1.6x 18 Zmotoryzowany napęd osi Z mikroskopu wraz ze śrubą nastawiania ostrości Motorized Z drive with focus knob 19 Automatyczny system utrzymywania stałej odległości pomiędzy obiektywem a preparatem, oparty na analizie odbicia światła w podczerwieni wysyłanego przez obiektyw na preparat. Hardware autofocus system based on reflection of IR light for keeping constant distance between objective and specimen in time-lapse experiments 20 Okular 10x, 2 sztuki 10x eyepiece, 2 pcs. 21 Wyświetlacz TFT zmotoryzowanych funkcji mikroskopu TFT screen for display of motorized functions 22 Stolik zmotoryzowany z enkoderami, kontrolerem i joystick iem, o przesuwie 110 x 75 mm w osiach xy, rozdzielczości (kroku) 20 ± 5 nm, niekolidujący w pełnym zakresie ruchu z inkubatorem skrzyniowym wymienionym w pkt 27, mogący pomieścić insert Piezo wymieniony w pkt. 24 Scanning xy stage with encoders, controller and joystick, travel range 110 x 75 mm, resolution (step) 20 ± 5 nm, non-colliding with cage incubator (given in #27) at any position; must hold Piezo insert given in #24 23 Insert na szalki wielodołkowe, pasujący do stolika zmotoryzowanego wymienionego w pkt. 22 i/lub do insertu Piezo wymienionego w pkt

17 Enclosure No 2 to the Terms of Reference Multi-well plate insert compatible with scanning stage given in #22 and/or Piezo insert given in #24 24 Insert Piezo o zasięgu 200 μm i powtarzalności 1 nm lub lepszej, do szybkiego obrazowania w osi Z, mogący pomieścić elementy wymienione w pkt Piezo insert with range 200 μm, reproducibility 1 nm or better, for fast scanning in Z; must hold components given in #25 and #26 25 Uniwersalny insert do szkiełek 3x1 i szalek Petriego 35-mm Universal insert for 3x1 slides and 35-mm Petri dishes 26 Mini-inkubator z przezroczystą pokrywą kompatybilną z kontrastem Nomarskiego, z dopływem mieszaniny gazów, z możliwością stabilnego zamocowania szalek Petriego 35-mm oraz komór do obrazowania z serii 40 firmy Warner Instruments o średnicy zewnętrznej 40 mm i wysokości 4.9 mm na brzegach Mini-incubator with transparent, DIC-compatible cover, with gas inlet; must stably hold 35-mm Petri dishes as well as imaging chambers from 40 series made by Warner Instruments, with outer diameter of 40 mm and height at edges of 4.9 mm 27 Przeźroczysty inkubator skrzyniowy umożliwiający regulację temperatury w zamkniętej przestrzeni wokół mikroskopu w zakresie od temperatury pokojowej do 40 C wraz z kontrolerem. Inkubator musi zapewniać swobodny i regulowany (np. drzwiczkami) dostęp do preparatu. Wymiary inkubatora muszą przewidywać miejsce na urządzenia zainstalowane na lewym i prawym porcie mikroskopu opisane w niniejszej specyfikacji technicznej. Transparent cage incubator with controller to keep stable temperature environment around the microscope from RT to 40 C. The incubator must allow easy and regulated (e.g. doors) access to specimen. Its dimensions must take into account the equipment installed at the left and right ports of the microscope, described in this technical specification. 28 Układ dostarczania nawilżonej mieszaniny powietrze-co 2 (zawartość CO 2 regulowana w zakresie 0-15 % lub większym) do miniinkubatora Module for humidified gas-mixture (0-15% CO 2 in air) delivery to the mini-incubator Skaner konfokalny oparty na technologii wirującego dysku Nipkowa (ang. spinning-disk) 17

18 Enclosure No 2 to the Terms of Reference wraz z kołem filtrów emisyjnych, dzielnikiem światła i dwiema kamerami EM-CCD do jednoczesnego obrazowania w dwóch kanałach spektralnych Confocal scanner based on Nipkow spinning-disk with emission filter wheel, a module for emission beam splitting and two EM-CCD cameras for simultaneous imaging in two spectral channels 29 Skaner konfokalny oparty na technologii wirującego dysku Nipkowa (ang. spinning-disk), zawierający jeden dysk z pinholami, drugi dysk z mikrosoczewkami, z następującymi podzespołami, funkcjami i parametrami: Confocal scanner based on Nipkow spinning-disk containing one disk with pinholes, second disk with microlenses, with the following subcomponents, functions and parameters: 30 Ilość pinholi na pierwszym dysku 20,000 Number of pinholes on first disk: 20, Średnica pojedynczej pinholi 50 µm Pinhole diameter 50 µm 32 Drugi dysk z mikrosoczewkami skupiającymi światło wzbudzania na pinholach Second disk with microlenses focusing excitation light on pinholes 33 Prędkość wirowania dysków, regulowana w zakresie od 1,500-5,000 rpm, umożliwiająca wykonanie do 1000 skanów na sekundę Disk rotation speed regulated from 1,500 to 5,000 rpm, allowing for up to 1000 scans per second 34 Możliwość ręcznej wymiany lustra dichroicznego Possibility to exchange dichroic mirror 35 Lustro dichroiczne poczwórne przepuszczalne dla światła wszystkich czterech laserów w systemie, i odbijające światło fluorescencji wzbudzanej przez te lasery Quad dichroic mirror transmissible for all lasers present in the system, and reflecting fluorescence light excited by those lasers 36 Zmotoryzowane koło filtrów emisyjnych zainstalowane na wyjściu skanera konfokalnego, z następującymi podzespołami, funkcjami i parametrami: Motorized emission filter wheel installed at scanner port, with the following subcomponents, functions and parameters: pozycji na filtry emisyjne o średnicy 25 mm 8-10 positions for emission filters with 25-mm diameter 38 Maksymalny czas przełączania filtrów emisyjnych w sąsiadujących pozycjach koła filtrowego: 35 ms Maximal switch time between adjacent positions in /podać nazwę producenta i /indicate producer and /podac nazwe producenta i /indicate producer and 18

19 Enclosure No 2 to the Terms of Reference filter wheel: 35 ms 39 Poczwórny filtr emisyjny o średnicy 25mm, odpowiedni do obrazowania DAPI, GFP, RFP i Cy5 Quad emission 25-mm filter suitable for DAPI, GFP, RFP and Cy5 40 Filtr emisyjny koła filtrowego o średnicy 25mm typu bandpass, o maksymalnej transmisji > 90% przy 450±3 nm, szerokość pasma 60±5 nm (dla DAPI), 25-mm emission bandpass filter with > 90% transmission at 450±3 nm, bandwidth 60±5 nm (for DAPI) 41 Filtr emisyjny koła filtrowego o średnicy 25mm typu bandpass, o maksymalnej transmisji > 90% przy 525±3 nm, szerokość pasma 30±5 nm (dla GFP) 25-mm emission bandpass filter with > 90% transmission at 525±3 nm, bandwidth 30±5 nm (for GFP) 42 Filtr emisyjny koła filtrowego o średnicy 25mm typu bandpass, o maksymalnej transmisji > 90% przy 615±5 nm, szerokość pasma 70±5 nm (dla RFP) 25-mm emission bandpass filter with > 90% transmission at 615±5 nm, bandwidth 70±5 nm (for RFP) 43 Polaryzator DIC do koła filtrowego DIC polarizer for filter wheel 44 Dzielnik światła rozdzielający światło emisji na dwie kamery, z następującymi podzespołami, funkcjami i parametrami: Module for splitting emission light onto two cameras, with the following subcomponents, functions and parameters: 45 Możliwość wymiany kaset z lustrami dichroicznymi Possibility to exchange cassettes with dichroic mirrors 46 Łatwe przestawianie pozycji kasety umożliwiające zmianę pomiędzy jednoczesnym obrazowaniem na dwóch kamerach i obrazowaniem 100% na jednej kamerze Easy change of cassette position between simultaneous imaging on two cameras and 100% imaging on single camera 47 Kaseta na lustro dichroiczne Dichroic mirror cassette 48 Lustro dichroiczne do kasety dzielnika światla do rozdziału światła przy 560 nm, filtr emisyjne dla /podać nazwę producenta i /indicate producer and 19

20 Enclosure No 2 to the Terms of Reference GFP i filtr emisyjny dla RFP/Cy5 do kasety dzielnika światła Dichroic mirror for beam splitting module to separate light at 560 nm, emission filter for GFP and emission filter for RFP/Cy5, for the cassette. 49 Pokrętła do regulacji położenia kasety, w celu łatwej rejestracji przestrzennej obrazów na obydwu kamerach Knobs for fine adjustment of cassette position to spatially align images on both cameras 50 Preparat testowy do kalibracji przestrzennej obrazów na kamerach Test specimen for spatial calibration of images on cameras 51 Adaptery do kamer EM-CCD z regulacją ogniskowania, o powiększeniu 1.2x, umożliwiające całkowite oświetlenie matrycy zainstalowanych kamer; 2 sztuki EM-CCD camera adapter with focus adjustment, magnification 1.2x, allowing for full illumination of installed EM-CCD chips, 2 pieces 52 Dwie identyczne kamery EM-CCD wraz z kablami i zasilaniem, zainstalowane na dzielniku światła, z następującymi podzespołami, funkcjami i parametrami dla pojedyńczej kamery: Two identical EM-CCD cameras together with cables and power supplies, installed at the beam splitting module, with the following subcomponents, functions and parameters of a single camera: 53 Wielkość piksela na matrycy: 8 μm Pixel size on chip: 8 μm 54 Ilość pikseli na matrycy: 1000 x 1000, lub więcej Number of pixels on chip: 1000 x 1000 or more 55 Możliwość zmiany szybkości odczytu w zakresie od MHz do MHz Possibility to change camera readout speed between MHz and MHz 56 Zakres przetwornika A/D: bit A/D converter: bit 57 Wydajność kwantowa przy długości fali 600 nm: 65% Quantum efficiency at 600 nm 65% 58 Przyłącze: C-mount Attachment via C-mount 59 Gniazdo i kabel do przesyłu danych do komputera Socket and cable for data transmission to the workstation 60 Możliwość synchronizacji pracy kamery z zewnętrznymi urządzeniami, w tym możliwość /podać nazwę producenta i /indicate producer and 20