1. Konferencje międzynarodowe:

1. Konferencje międzynarodowe: 1.1. Antazoline - new effective antiarrhythmic drug for acute termination of atrial fibrillation. Insights into druginduced electrocardiographic and haemodynamic effects. Roman Piotrowski, Joanna Giebułtowicz, Jakub Baran, Agnieszka Sikorska, Dagmara Gralak-Łachowska, Małgorzata Soszyńska, Magdalena Misiewicz, Elżbieta Błachnio, Piotr Wroczyński, Piotr Kułakowski. Cardiostim - EHRA EUROPACE 2016, Nicea, France 1.2. Development of novel extraction method of 2-aminothiazoline-4- carboxylic acid on highly selective molecularly imprinted sorbent from post mortem blood. Joanna Giebułtowicz, Monika Rużycka, Piotr Luliński, Dorota Maciejewska, Piotr Wroczyński. 18 th International Symposium on advances in extraction technologies & 22 nd International Symposium on Separation Science 2016, Toruń, Poland 1.3. Enantioselective analysis of plasma free amino acid in renal transplant recipients using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS). Emilia Krzemińska, Joanna Giebułtowicz, Aleksandra Wyczałkowska Tomasik, Leszek Pączek, Piotr Wroczyński. 18 th International Symposium on advances in extraction technologies & 22 nd International Symposium on Separation Science 2016, Toruń, Poland 1.4. Determination diagnostic value of uremic toxins in saliva using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS). Joanna Giebułtowicz, Bartłomiej Sankowski, Natalia Korytowska, Aleksandra Wyczałkowska Tomasik, Leszek Pączek, Piotr Wroczyński. 18 th International Symposium on advances in extraction technologies & 22 nd International Symposium on Separation Science 2016, Toruń, Poland 1.5. Development and validation of a LC-MS/MS method for quantitative analysis of unbound fractions of p-cresol sulphate and indoxyl sulphate in serum using a cloud point extraction (CPE). Martyna Chechłacz, Natalia Korytowska, Joanna Giebułtowicz. 12th Warsaw International Medical Congress 2016, Warsaw, Poland

1.6. The influence of the variability of ALDH3A1 sequence on the risk of senile cataract. Karolina Nowakowska, Joanna Giebułtowicz, Mariusz Berdyński, Piotr Krawczyk. 12th Warsaw International Medical Congress 2016, Warsaw, Poland 1.7. The comparison of cyanide and carboxyhemoglobin concentrations obtained from post mortem blood from fire victims from Mazovia with results gained from literature review. Edyta Hedinger, Agnieszka Gryglak, Monika Rużycka, Joanna Giebułtowicz. 11th Bialystok International Medical Congress 2016, Białystok, Poland 1.8. The level of 2-aminothiazoline-4-carboxylic acid- a new cyanide exposure marker in post mortem blood of fire victims. Monika Rużycka, Joanna Giebułtowicz, Anna Stec, Marcin Fudalej, Paweł Krajewski, Piotr Wroczyński. FireTox 2016, Preston, United Kingdom 1.9. The application of a new HPLC-FL method in determination of ALDH1 activity in plasma and serum. Karolina Księżarczyk, Sandra Sieczkowska, Sylwia Michorowska, Agnieszka Wiśniewska, Piotr Wroczyński, Joanna Giebułtowicz, Riga Stradins University International Student Conference 2016, Ryga, Latvia 1.10. Is keratoconus risk associated with genetic variation of aldehyde dehydrogenase ALDH3A1 gene? Piotr Krawczyk, Jean-Marc Perone, Anna Ambroziak, Joanna Giebultowicz, Oualid Guechi, Adina Agapie, Nadia Ouamara, Louis Lhuillier, Naïla Houmad, Huong Duong Nguyen Viet, Jacek Szaflik. Annual Meeting of the Association for Research in Vision and Ophthalmology 2016, Baltimore, USA 1.11. Est-ce que le risque du kératocône est associé a la variation génétique du gène de l aldéhyde déshydrogénase ALDH3A1. Piotr Krawczyk, Jean-Marc Perone, Anna Ambroziak, Joanna Giebułtowicz, Jacek Szaflik. 22e Congrès de la Société Française d Ophtalmologie 2016, Paris, France 1.12. Antazoline effective antiarrhythmic drug for acute termination of atrial fibrillation. Insights into drug-induced electrocardiographic and haemodynamic effects. Roman Piotrowski, Joanna Giebułtowicz, Jakub Baran, Agnieszka Sikorska, Dagmara Gralak-Łachowska, Małgorzata

Soszyńska, Magdalena Misiewicz, Elżbieta Błachnio, Piotr Wroczyński, Piotr Kułakowski. 20th International Congress of the Polish Cardiac Society 2016, Poznan, Poland 1.13. Old Dog, New Tricks In Silico Charakterization of Antazoline Cardiac Safety. Sebastian Polak, Bartosz Lisowski, Bogna Badyra, Roman Piotrowski, Piotr Kułakowski, Joanna Giebułtowicz, Piotr Wroczyński, Barbara Wiśniowska. Computing in Cardiology 2016, Vancouver, Canada 1.14. Determination of pharmaceutically active compounds in the organisms from the Vistula and Utrata rivers. Łukasz Schreyer, Joanna Giebułtowicz, Agata Drobniewska, Grzegorz Nałęcz-Jawecki. EcoBalt 2016, Tartu, Estonia 1.15. Comparison of antioxidant status in saliva and plasma of healthy pregnant women and in pregnancy complicated with gestational diabetes. Agata Majewska, Alicja Karzecka, Martyna Micek, Joanna Giebułtowicz, Małgorzata Sochacka, Przemysław Kosiński, Aneta Zwierzchowska, Radosław Rodzoch, Mateusz Rzentała, Bartosz Leończak. 11th Warsaw International Medical Congress for Young Scientists 2015, Warsaw, Poland 1.16. The application of a new HPLC-FL method in determination of ALDH1 activity in plasma and serum. Karolina Księżarczyk, Sandra Sieczkowska, Sylwia Michorowska, Agnieszka Wiśniewska, Piotr Wroczyński, Joanna Giebułtowicz, Third Conference Integration of Pharmacogenomics in clinical decision support 2015, Budapest, Hungary 1.17. Application of LC-MS/MS method for quantitative analyses of uremic toxins p-cresol, sulfate and indoxyl sulfate in saliva. Bartłomiej Sankowski, Natalia Korytowska, Joanna Giebułtowicz, Piotr Wroczyński. 26th European Students Conference 2015, Berlin, Germany 1.18. Heavy metals content in Spirulina and Chlorella supplements available on Polish market. Karolina Osucha, Trustees of the paper: Joanna Giebułtowicz, Małgorzata Sochacka. 11th Warsaw International Medical Congress for Young Scientists 2015, Warsaw, Poland 1.19. Development and validation of LC-MS/MS method for quantitative analyses of p-cresol sulfate and indoxyl sulfate in human saliva. Bartłomiej

Sankowski, Natalia Korytowska, Joanna Giebułtowicz. 11th Warsaw International Medical Congress for Young Scientists 2015, Warsaw, Poland 1.20. Mossbauer spectroscopy as a tool for the assessment of the concentration of iron in brain samples. Przemysław Duda, Joanna Giebultowicz, Małgorzata Sochacka, Andrzej Friedman, Jolanta Galazka- Friedman. International Conference on the Applications of the Mossbauer Effect 2015, Hamburg, Germany 2. Konferencje krajowe: 2.1. Pharmacokinetic study of antazoline mesylate after intravenous administration in humans. Joanna Giebułtowicz, Roman Piotrowski, Jakub Baran, Piotr Kułakowski, Piotr Wroczyński, X Multidisciplinary Conference on Drug Research 2016, Korytnica, Polska 2.2. Ocena całkowitego potencjału antyoksydacyjnego oraz wybranych markerów niewydolności nerek. Alicja Olejnik, Kinga Wilk, Natalia Korytowska, Joanna Giebułtowicz, Piotr Wroczyński. III Ogólnopolska Konferencja Studentów Medycyny Laboratoryjnej i Młodych Diagnostów Wschodząca Diagnostyka 2016, Białystok, Polska 2.3. Cytologiczne efekty działania organicznej formy selenu (Selolu) na rośliny dziurawca (Hypericum perforatum L.) poddanego stresowi kadmem. Joanna Ślusarczyk, Joanna Giebułtowicz, Mieczysław Kuraś, Piotr Wroczyński. 57. Zjazd Polskiego Towarzystwa Botanicznego 2016, Lublin, Polska 2.4. Przykład zastosowania spektrometrii Mössbauerowskiej do wyznaczania zawartości żelaza w próbce liofilizowanej tkanki mózgowej. Paulina Rzepecka, Przemysław Duda, Joanna Giebułtowicz, Małgorzata Sochacka, Andrzej Friedman, Jolanta Gałązka-Friedman. XI Ogólnopolskie Seminarium Spektroskopii Mössbauerowskiej 2016, Turno, Polska

3. Publikacje (wszystkie z 2015 i czesc z 2016 roku została podana do rozliczenia w zeszłym roku): 1.1. Giebułtowicz J.*, Kojro G., Buś-Kwaśnik K., Rudzki P.J., Marszałek R. Leś A., Wroczyński P. (2015) Cloud-point extraction is compatible with liquid chromatography coupled to electrospray ionization mass spectrometry for the determination of bisoprolol in human plasma. Journal of Chromatography A 1423:39-46 1.2. Stankiewicz A., Giebułtowicz J.* Stefański M., Sikorska K., Wroczyński P., Nałęcz- Jawecki G. (2015) The development of the LC-MS/MS method based on S-9 biotransformation for detection of metabolites of selected β-adrenolytics in surface water. Environmental Toxicology and Pharmacology 39(2):906-916 1.3. Luliński P., Giebułtowicz J., Wroczyński P., Maciejewska D. (2015) A highly selective molecularly imprinted sorbent for extraction of 2-aminothiazoline-4- carboxylic acid Synthesis, characterization and application in post-mortem whole blood analysis. Journal of Chromatography A 1420:16-25 1.4. Giebułtowicz J.*, Nałęcz-Jawecki G. (2016) Occurrence of immunosuppressive drugs and their metabolites in the sewage-impacted Vistula and Utrata Rivers and in tap water from the Warsaw region (Poland). Chemosphere 148:137-147 1.5. Giebułtowicz J.*, Korytowska N., Sankowski B., Wroczyński P. (2016) Development and validation of a LC-MS/MS method for quantitative analysis of uraemic toxins p-cresol sulphate and indoxyl sulphate in saliva. Talanta 150:593-598 1.6. Giebułtowicz J.*, Rużycka M., Fudalej M., Krajewski P. Wroczyński P. (2016) LC- MS/MS method development and validation for quantitative analyses of 2- aminothiazoline-4-carboxylic acid a new cyanide exposure marker in post mortem blood. Talanta 150:586-592 1.7. Wyczalkowska-Tomasik A., Czarkowska-Paczek B., Giebultowicz J., Wroczynski P., Paczek L. (2016) Age-dependent increase in serum levels of indoxyl sulphate and p- cresol sulphate is not related to their precursors: Tryptophan and tyrosine. Geriatrics and Gerontology International doi: 10.1111/ggi.12811 1.8. Giebułtowicz J.*, Kojro G., Piotrowski R., Kułakowski P., Wroczyński P. (2016) Cloud-point extraction is compatible with liquid chromatography coupled to

electrospray ionization mass spectrometry for the determination of antazoline in human plasma. Journal of Pharmaceutical and Biomedical Analysis 128:294-301 1.9. Giebułtowicz J.*, Piotrowski R., Baran J., Kułakowski P., Wroczyński P. (2016) Application of a novel liquid chromatography/tandem mass spectrometry method for the determination of antazoline in human plasma: Result of ELEPHANT-I [ELEctrophysiological, pharmacokinetic and hemodynamic effects of PHenazolinum (ANTazoline mesylate)] human pharmacokinetic study 1.10. Giebułtowicz J.*, Stankiewicz A., Wroczyński P., Nałęcz-Jawecki G. (2016) Occurrence of cardiovascular drugs in the sewage-impacted Vistula River and in tap water in the Warsaw region (Poland). Environmental Science and Pollution Research DOI: 10.1007/s11356-016-7668-z